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Internet2 Partnerships with Advanced Global Networks in the Health Sciences

Internet2 Partnerships with Advanced Global Networks in the Health Sciences. Ana Preston Internet2 International Relations Program Manager apreston@internet2.edu Mary Kratz, MT(ASCP) Internet2 Health Sciences Program Manager Mkratz@internet2.edu

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Internet2 Partnerships with Advanced Global Networks in the Health Sciences

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  1. Internet2 Partnerships with Advanced Global Networks in the Health Sciences Ana PrestonInternet2 International Relations Program Manager apreston@internet2.edu Mary Kratz, MT(ASCP) Internet2 Health Sciences Program Manager Mkratz@internet2.edu Instituto De Investigaciones Biomedicas “Alberto Sols” Madrid, February 2004

  2. Agenda • Who is this person with the funny accent…Ana • What is Internet2? • Cyberinfrastructure • Security • Programs • Future Networks • International Partnerships • Who is this person without the spanish…Mary • Internet2 Health Sciences • NIH Roadmap • Medicine meets Internet2 2004 Priorities and Cyberinfrastructure • Medical Applications 2 12/08/03

  3. What is Internet2? • Mission: develop and deploy advanced network applications and technologies, accelerating the creation of tomorrow’s Internet • University • Government • Industry 3 12/08/03

  4. Internet2 today • 205 regular university members, 66 Corporate members, and 41 Affiliate members • Expanded access: over 30 state-based education networks across the nation • 45 International partners, over 27 peer networks extending Internet2 backbone network to 50+ countries 4 12/08/03

  5. Committed to Core Values • Address the advanced networking needs and interests of the research & education community • Provide leadership to evolve the global Internet • Leverage strategic relationships among academia, industry and government • Catalyze activities that cannot be accomplished by individual organizations • Implement a systems approach towards a scalable and vertically integrated advanced networking infrastructure

  6. Internet2 2004 Priorities • Engage with Cyberinfrastructure • New pathways to discovery • Security • Availability of production infrastructure to develop and deploy • Network infrastructure • Application development and deployment • Research teams of the future • Future network capabilities

  7. Cyberinfrastructurehttp://www.cise.nsf.gov/evnt/reports/toc.htmCyberinfrastructurehttp://www.cise.nsf.gov/evnt/reports/toc.htm • “…multiple accelerating trends are converging…in ways that show extraordinary promise for an even more profound and rapid transformation…”[NSF] • Ubiquitous networking • Interoperability of information formats and access • Creation of comprehensive knowledge environments • Unprecedented capacity for computation, storage, and communication

  8. Components of CyberInfrastructure-enabled science & engineering High-performance computing for modeling, simulation, data processing/mining People Instruments for observation and characterization. Individual & Global Connectivity Physical World Group Interfaces & Visualization Facilities for activation, manipulation and Collaboration construction Services Knowledge management institutions for collection building and curation of data, information, literature, digital objects Source: Paul Messina – Fall 2003 Internet2 member meeting, “Cyberinfrastrucutre: Promises and Challenges” presentation at http://www.internet2.edu/presentations/fall-03/20031014-Plenary-Messina.htm

  9. Middleware is the stuff that makes “transparent use” happen, providing persistency, consistency, security, privacy, and capability Middleware : Security http://middleware.internet2.edu

  10. Internet2 community National Middleware Initiative • Common infrastructure for inter-institutional authentication/authorization • Development of Shibboleth tool • Trust federation: InCommon • Security • Network security, host software, and middleware become inter-dependent • Security at “Line Speed”

  11. Production Infrastructure: AbileneCore Map, November 2003 • Backbone operates at 10 Gbps (OC192) • 11 core nodes • 31 GigaPoPs Regional high-performance aggregation sites • Local campus networks provide 100 Mbps to the desktop

  12. Internet2 Network Infrastructure • End to end performance initiative • Measurement/monitoring network http://abilene.internet2.edu/observatory/ • New architectures/common infrastructure http://e2e.internet2.edu • Optical networking efforts • Facility-based networking • Owned assets (vs. bought telecom services) • Beyond the GigaPoP to endpoints 12 12/08/03

  13. Research Optical Networks(RON) • Fiberco • Supporting project: designed to support optical initiatives (regional and national) • Holding and assignment vehicle (will not light fiber) • National LambdaRail (NLR) • National leased/owned facility • Largest higher-edu owned/managed optical networking & research facility in the world (~10,000 route-miles of dark fiber) • Four 10-Gbps ’s provisioned at outset • One  allocated to Internet2 • Experimental platform for research • Differentiated set of networks

  14. Available fiber topology

  15. Global  Integration Facility (GLIF) • Dedicated lightpaths • Circuit switched sub- ’s • Link HPC resources internationally • Leadership: • StarLight (Chicago) • CA*Net (Canada) • SURFnet (Netherlands) • Other participants: • Internet2 entering efforts • NORDUnet (Scandinavia) • Czech Republic • Japan

  16. Hybrid Optical Packet Infrastructure (HOPI) • Converging worlds • High-performance national IP network (Abilene) • Regional Optical Networks (RON) • National optical capabilities (NLR) dedicated to Internet2 • International collaboration efforts and leadership (GLIF) • HOPI design team (just convened) • Architecture • Implementation plan • Towards a 3rd generation Internet2 network architecture; the prelude

  17. More information • http://abilene.internet2.edu • http://abilene.internet2.edu/observatory • http://ipv6.internet2.edu • http://www.fiberco.org • http://www.nationallambdarail.org • A HOPI site to be announced in the near future • Stay tuned for … Medical Optical Overlay Networks (“MOON”) 

  18. International Focus • Build effective partnerships • Organizations with similar goals/objectives and constituencies • Enable global collaboration • Mechanism: Memoranda of Understanding(MoU) • Provide/promote interconnectivity between communities • Collaborate on technology development and deployment • Engagement to: • Establish leading, high-performance network infrastructures • Ensure global coordination • End-to-end performance in support of R&E communities

  19. Last updated: 04 January 2004 Countries reachable via Internet2’s Abilene network Europe-Middle East Asia-Pacific Americas Austria (ACOnet) Belgium (BELNET) Croatia (CARNet) Czech Rep. (CESNET) Cyprus (CYNET) Denmark (Forskningsnettet) Estonia (EENet) Finland (Funet) France (Renater) Germany (G-WIN) Greece (GRNET) Hungary (HUNGARNET) Iceland (RHnet) Ireland (HEAnet) Israel (IUCC) Italy (GARR) Latvia (LATNET) Lithuania (LITNET) Luxembourg (RESTENA) Malta (Univ. Malta) Netherlands (SURFnet) Norway (UNINETT) Poland (POL34) Portugal (RCTS2) Qatar (Qatar FN) Romania (RoEduNet)Russia (RBnet) Slovakia (SANET) Slovenia (ARNES) Spain (RedIRIS) Sweden (SUNET) Switzerland (SWITCH) United Kingdom (JANET) Turkey (ULAKBYM) *CERN Australia (AARNET) China (CERNET, CSTNET, NSFCNET) Hong Kong (HARNET) Japan (SINET, WIDE, IMNET, JGN) Korea (KOREN, KREONET2) Singapore (SingAREN) Philippines (PREGINET) Taiwan (TANet2, ASNet) Thailand (UNINET, ThaiSARN) Argentina (RETINA) Brazil (RNP2/ANSP) Canada (CA*net) Chile (REUNA) Mexico (Red-CUDI) United States (Abilene, vBNS) Venezuela (REACCIUN-2) http://abilene.internet2.edu/peernetworks/international.html

  20. Last updated: 2 January 2004 Abilene International Peering

  21. International connectivity • Internet2 backbone networks primarily US • Partner networks pay to get to the US • NSF provides some funding for international links/interconnection points • TransPAC (Asia/Pacific Rim) • EuroLink (Europe) • NAUKAnet (Russia) • STAR TAP/Star Light (Chicago) • AMPATH • Other international exchange points/transit facilitated by Internet2 members • Transit inside the US provided by Internet2

  22. Spain’s National Research and Education Network • RedIRIS • 2.5 Gbps backbone network • Ministry of Science and Technology (1988) • Over 250 universities and research centers • Connected to GEANT (pan-European network) at 10 Gbps • GEANT to North America

  23. Europe • Pan-European network: GEANT: • 31 countries connecting • Operated by DANTE; 10 Gbps core • Total of 4x2.5Gbps + 2x1Gbps across Atlantic (DANTE & EuroLink provided) • Connecting Europe to other regions of the world • ALICE, EUMEDCONNECT 24

  24. North Cluster (CN, JP, KR, …) Europe North America Central Asia Net South Asia Net West Asia Net Southeast Cluster (MY, SG, TH,…) Oceania Cluster (AU,…) Asia-Pacific Russia Japan Korea USA China • Taiwan Hong Kong Thailand Vietnam Philippines Malaysia • Sri Lanka Singapore Indonesia Exchange Point Access Point Current status 2003 (plan) Trends: - China, Japan, Korea - Singapore, Australia • Australia 25

  25. Africa/Middle East/South and Central Asia • No dedicated R&E network connectivity from African continent • Some national inter-university connections: South Africa, Egypt, and Morocco • EUMEDconnect • Mediterranean countries – including North African countries • Connection to GEANT • Middle-East • Turkey, Israel: Connected to GEANT • Persian Gulf: Qatar • South and Central Asia • Virtual Silk project – Central Asia • India, Bangladesh, Sri Lanka, Pakistan – no connectivity

  26. Americas • Canada, Mexico, US cross-border connectivity • Chile, Venezuela, Brazil, Argentina connected to Miami via 45Mpbs (AMPATH) • Cable infrastructure around the region • CLARA backbone network emerging Latin America and Caribbean(16 countries) 27

  27. Healthcare in the Information Age

  28. The scope of the Internet2 Health Science Workgroup includes clinical practice, medical and related biological research, education, and medical awareness in the public.

  29. Key Internet2 Health Science Members (just a sampling) • 86 Academic Medical Centers (AAMC) • Stanford, Harvard, Ohio State, UIC, Northwestern, UPenn, etc. • 130 Health Science related colleges • Public Health, Nursing, Dentistry, Pharmacy, Social Work • Affiliates • NIH, FDA, NSF, NASA, NOAA • Howard Hughes Medical Institute, Oak Ridge National Lab, etc. • Big Pharma • Johnson&Johnson, Pfizer, Eli Lilly • TeleHealth • Prous Science • Cisco, IBM, Microsoft, SUN, Polycom, etc. • Ford Motor Company

  30. Why Physicians Participate in Internet2 • Extend the provision of better healthcare • TeleHealth (eHealth) • National Tumor Board • Develop Clinical Skills and Assessment (AAMC partnership) • Distributed data sharing • Electronic Health Record • Presence and Integrated Communications (VoIP, RFID) • Advanced visualization Computer Aided Diagnosis • Computer Assisted Surgery (Minimally invasive surgery) • Collaboration independent of boundaries • Geography: Second Opinion Networks • Time: Learning Technology (Distance Education) • Computation: Knowledge Management

  31. Why Researchers Participate in this community Internet2 doesn't only save time, it allows interactivity in places where that was not possible before. I'd call it a quantum leap, if I didn't know that physics defines that as the smallest change a system is capable of... Timothy Poston, Bangladesh

  32. Why Educators Participate in Internet2 • Rich resources from student endpoints to centralized powerful computation and large storage • Students absorb multiple channels of information Dynamic charts Second screen lecture Communal note taking messaging • Slide courtesy: • Parvati Dev, Stanford University

  33. NIH Roadmap “Science is evolving at an incredible pace. It’s a revolutionary period. The fundamental change is that biomedical science has converged…. You have to almost consciously say, O.K. how do we take this into account”.E. Zerhouni, M.D.Director, National Institutes of HealthThe New York Times (July 15th, 2003)

  34. NIH Roadmap: 3 questions • What are today’s most pressing scientific challenges? • What are the roadblocks to progress and what must be done to overcome them? • Which efforts are beyond the mandate of one or a few…but are the responsibility of (NIH as) a whole?

  35. NIH Roadmap: Implementation Themes • New Pathways to Discovery • National Technology Centers • Molecular knowledgebase/Bioinformatics • Nanomedicine • Research Teams of the Future • Team Science • Reengineering Clinical Research Enterprise • Integration/interoperability • National Electronic Clinical Trials and Research (NECTAR) Network • Translational Research Services and Centers

  36. Internet2 2004 Priorities: Health Science Perspectives • Engage with Cyberinfrastructure • NIH Roadmap: Pathways to Discovery • Security initiatives to enable Internet2 applications and leverage network capabilities • Federal Legislation: HIPAA • Availability of production infrastructure for development and deployment migration • NIH Roadmap: Research Teams of the Future • Enhance Internet2’s role as a leader in advanced networking • NIH Roadmap: Reengineering Clinical Research Enterprise

  37. Roadmap • Networking Health:Prescriptions for the Internet • National Research Council Report • Current and future Internet • Released 24 February 2000 • National Academy Press • ISBN 0-309-06843-6

  38. Pathways to Discovery: BISTI Biomedical Information Science and Technology Initiative (BISTI) • Facilities (Laboratories) • People (Scientists) • Knowledge (Bioinformatics) • NIH leadership initiated in 1999 • http://www.bisti.nih.gov

  39. Research Team of the Future: BECON • Team Science • Multi-disciplinary • Trans-disciplinary • Plus • Better Science • Resource sharing • Reduce costs • Minus • Collaboration “Tax” • Resource ownership • Governance

  40. Reengineering the Clinical Research Enterprise: NHII

  41. Cyberinfrastructurehttp://www.cise.nsf.gov/evnt/reports/toc.htmCyberinfrastructurehttp://www.cise.nsf.gov/evnt/reports/toc.htm • Enterprise • Informatics • Computation • Engineering • Technology

  42. Biomedical Informatics Research Network (BIRN) Funded by: NCRR/NIH Mark Ellisman, PhD,Univ. California San Diego, SDSC http://www.nbirn.net/

  43. Biomedical Informatics Research Network (BIRN) • Neuroscience initial focus • High bandwidth • Inter-institutional connectivity via Internet2 • Uniformly consistent security model • Grid computing • Distributed (federated) file management and computational services • Performance and resiliency for databases • Integrated visualization and analysis tools

  44. EACH BRAIN REPRESENTS A LOT OF DATA AND COMPARISONS MUST BE MADE BETWEEN MANY (fMRI) Slide courtesy of Arthur Toga (UCLA)

  45. Time Needed to Move Brain Images Across the Internet Voxel size: 1 mmImaging Technology: Current color MRIData generated: 4.5 Megabytes 643 seconds 56 Kbps Modem 36 seconds Broadband Internet 0.4 seconds Typical LAN 0.006 seconds Current Internet2 Record (5.6 Gbps)

  46. Time Needed to Move Brain Images Across the Internet Voxel size: 10 µmImaging Technology: Current color fMRI Data generated: 4.5 Terabytes 178,571 hours 56 Kbps Modem 10,000 hours Broadband Internet 100 hours Typical LAN 1.8 hours Current Internet2 Record (5.6 Gbps)

  47. Time Needed to Move Brain Images Across the Internet Voxel size: 1 µmImaging Technology: Near-future color fMRIData generated: 4.5 Petabytes 1,062,925.17 weeks 56 Kbps Modem 59,523.8 weeks Broadband Internet 181.7 weeks Typical LAN 10.6 weeks Current Internet2 Record (5.6 Gbps)

  48. Health Science Grand Challenge <Organism(person)><Organ><Tissue><Cell><Protein><Atom>(1m) (10-3m) (10-6m) (10-9m) (10-12m) (10-15m) Systems models Continuum models (PDEs) ODEs Stochastic models Pathway models Gene networks Courtesy: Peter Hunter, University of Auckland

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