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Tissue Sourcing. ENGI NEERI NG. BASIC PROCESS CONSIDERATIONS Tissue Sourcing: obtain informed consent iPSC generation: approval of license (ie. iPS Academia Japan, Inc) Vectors: use episomal plasmids or integration-free methods
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Tissue Sourcing ENGI NEERI NG • BASIC PROCESS CONSIDERATIONS • Tissue Sourcing: obtain informed consent • iPSC generation: approval of license • (ie. iPS Academia Japan, Inc) • Vectors: use episomal plasmids or • integration-free methods • Engineering: use open source TALENs or • license technology • Processing differentiated cells: acquire • license • Delivery Method: device to inject cells • PSC derivation SORT ING • PSC derived product manufacture • PSC Differentiation • Preclinical studies • Cells in Assay format • Clinical studies • Appropriate Screen • BMLA license and commercialization • Commercial Partner