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Creating an AIDS-Free Generation The beginning of the end of AIDS. Center for Strategic & International Studies Washington, DC March 22, 2012. Thomas R. Frieden , MD, MPH Director Centers for Disease Control and Prevention. 2012 is a tipping point for the global HIV epide mic.
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Creating an AIDS-Free GenerationThe beginning of the end of AIDS Center for Strategic & International Studies Washington, DC March 22, 2012 Thomas R. Frieden, MD, MPH Director Centers for Disease Control and Prevention
2012 is a tipping point for the global HIV epidemic • Increasing coverage, decreasing costs • Recognition of global shared responsibility and accountability • New evidence that • Treatment is prevention • PMTCT and voluntary male medical circumcision can be scaled up for population reach and impact • Infection rates and deaths can be driven down
Global Disease Detection Centers DoD Collaborations CDC Direct Assignees CDC Field Epidemiology Training Program (FETP) CDC Malaria Assignees CDC Influenza International Assignees CDC Global AIDS Program CDC provides assistancethroughout the world Global Immunizations Assignees • Nearly 400 assignees in 50+ countries 1,500 host country national staff
5 4 Number (millions) 3 2 1 0 1990 1993 1996 1999 2002 2005 2008 Global Sub-Saharan Africa HIV incidence is decreasingNumber of people newly infected with HIV,globally and in Sub-Saharan Africa, 1990-2008 Source: UNAIDS/WHO
3.0 2.5 2.0 Number (millions) 1.5 1.0 0.5 0 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 Global Sub-Saharan Africa HIV-related mortality is also decliningNumber of AIDS-related deaths, globally and inSub-Saharan Africa, 1996-2008 Source: UNAIDS/WHO
U.S. government calls for anAIDS-free generation AIDS-free generation • Virtually no children born with HIV infection • Adults living with HIV don’t develop AIDS • Accelerated declines in HIV incidence Combination prevention • Antiretroviral treatment as prevention • Prevention of mother-to-child transmission (PMTCT) • Voluntary medical male circumcision • Correct & consistent condom use
National HIV/AIDS Strategy for the United States • Reduce new HIV infections • Increase access to care and improve health outcomes for people living with HIV • Reduce HIV-related disparities andhealth inequities • Achieve a more coordinatednational response to the HIV epidemic
New CDC approach to HIV preventionin the U.S. Funding to places most in need, for populations most in need, for programs that work • Funding determined by number of people living with HIV • Supports innovative demonstration programs by Health Departments • 75% of proposed activities in 4 program areas • HIV testing and linkage to care • Comprehensive HIV Prevention with Positives • Condom distribution • Initiatives to promote prevention and accountability, particularly viral load
Effective prevention interventionsCoverage of these evidence-based interventions remains limited
Adult male circumcision provides long-lasting protection against HIV infectionRakai, Uganda
Modeling combination prevention and reductions in HIV incidenceIncidence in Swaziland in 2014 by scenario ART = antiretroviral treatment MC = male circumcision
Sustainable public health progressCDC helps develop local capacity domestically & globally • Guidance, technical assistance, direct funds • Applied epidemiology • US direct hires and host country national staff • Labs systems and quality • Health security
Centers for Disease Control and Prevention 1600 Clifton Road NE, Atlanta, GA 30333 Phone: 1-800-CDC-INFO (232-4636)/TTY: 1-888-232-6348 E-mail: cdcinfo@cdc.gov Web: www.cdc.gov