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AIM : What are Pedigree Charts ?

Learn how to construct and interpret pedigree charts to analyze the genetic history of a family and identify the likelihood of a child inheriting a disorder. Understand the difference between autosomal and X-linked diseases.

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AIM : What are Pedigree Charts ?

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  1. Do Now : Think-Pair-Share For a height characteristic when tall is dominant What would be the phenotypic ratio for offspring of heterozygous and homozygous recessive parents? AIM : What are Pedigree Charts ?

  2. What is a Pedigree? • A pedigree is a chart of the genetic history of family over several generations. • Scientists or a genetic counselor would find out about your family history and make this chart to analyze.

  3. Constructing a Pedigree • Male • Female

  4. Connecting Pedigree Symbols Examples of connected symbols: • Married Couple • Children

  5. Example • What does a pedigree chart look like?

  6. Symbols in a Pedigree Chart

  7. Interpreting a Pedigree Chart • Determine whether the disorder is dominant or recessive. • If the disorder is dominant, one of the parents must have the disorder. • If the disorder is recessive, neither parent has to have the disorder because they can be heterozygous.

  8. Example of Pedigree Charts • Dominant or Recessive?

  9. Answer • Dominant

  10. Example of Pedigree Charts • Dominant or Recessive?

  11. Answer • Recessive

  12. Interpreting a Pedigree Chart • Determine if the pedigree chart shows an autosomal or X-linked disease. • If most of the males in the pedigree are affected the disorder is X-linked • If it is a 50/50 ratio between men and women the disorder is autosomal.

  13. Types of Chromosomes Autosomal gene- a gene found on any chromosome except for the sex chromosome. These are chromosomes numbered 1-22. X-linked gene- a gene found on a chromosome designated as a sex chromosome (X or Y).

  14. Answer • Autosomal

  15. Answer • Autosomal

  16. Example of pedigree • Is it Autosomal or X-linked?

  17. Answer X- linked

  18. Example of Pedigree • Is it Autosomal or X-linked?

  19. Answer Autosomal

  20. Summary • Pedigrees are family trees that explain your genetic history. • Pedigrees are used to find out the probability of a child having a disorder in a particular family. • To begin to interpret a pedigree, determine if the disease or condition is autosomal or X-linked and dominant or recessive.

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