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CASE 1 . 5 1 yo man IVDU in past….last used 25 yrs ago Stable social situation Currently employed with private health coverage No comorbid disease. CASE 1 . Hepatitis C disease parameters Secondary workup negative…no co-infections HCVRNA 1.89 x 10E6 iu /ml Mixed genotypes 1 and 4
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CASE 1 • 51 yo man • IVDU in past….last used 25 yrs ago • Stable social situation • Currently employed with private health coverage • No comorbid disease
CASE 1 Hepatitis C disease parameters • Secondary workup negative…no co-infections • HCVRNA 1.89 x 10E6 iu/ml • Mixed genotypes 1 and 4 • Biopsy reveals F3 scarring and moderate activity • Imaging unremarkable
CASE 1 Questions • Would you treat? • Does activity of inflammation play a role in your decision making in an individual • 3rd agent preference? • Is response guided therapy with DAAs appropriate here?