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Beau

Beau. A case report. Signalment:. 11 year old Male Castrated Border collie. History.

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Beau

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  1. Beau A case report

  2. Signalment: • 11 year old • Male Castrated • Border collie

  3. History • 12/29/06 referring veterinarian noticed lymphadnopathy. Blood work was unremarkable and the urinalysis showed RBCs. He was placed on deramaxx for arthritis (per owners Beau was slowing down) and doxycycline. • 1/8/07 Beau was not improving. Along with the lymphadnopathy he now had bruising on his abdomen. Lymph node biopsies : only showed lymphoid hyperplasia and panniculitis. Coag panel was normal although his platelet numbers had dropped from 314,000 to 171,000. Deramaxx was stopped. • Beau continued to decline and was referred to NCSU-CVM 2/21/07.

  4. PE • Temp: 103.6 • BCS: 4/9 • Diffuse marked lymphadenopathy

  5. CBC • Normocytic normochromic nonregenerative anemia • Lymphopenia • Monocytopenia

  6. Lymph node aspirate • > 50% Lymphoblast • Multinucleated lymph cells

  7. Thoracic radiographs • Sternal and tracheobronchial lymphomegaly

  8. Ultrasound • Infiltrative splenic disease

  9. Ultrasound • Diffuse lymphadenopathy

  10. Stages of Lymphoma • Stage I: Only one lymph node involved. • Stage II: Regional LNs, limited to one side of diaphragm • Stage III: All peripheral LNs • Stage IV: All peripheral LNs plus spleen, liver, and/or anterior mediastinum. • Stage V: Everything in stage IV plus bone marrow involvement.

  11. Staging Lymphoma • The stage of the disease does not impact the response to chemotherapy. • So stage II may not have a better prognosis than stage IV. • The exception is stage V which has a poor response to chemotherapy.

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