1 / 1

200

1000. 1400. centre>peripheral. 1200. 500. 1000. PGE 2. pg/mg. 800. 0. 600. peripheral>central. 400. -500. 200. 0. -1000. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. centre>peripheral. COX-2 IHC. arbitrary units. 40.

betha
Download Presentation

200

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 1000 1400 centre>peripheral 1200 500 1000 PGE2 pg/mg 800 0 600 peripheral>central 400 -500 200 0 -1000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 centre>peripheral COX-2 IHC arbitrary units 40 peripheral>central 20 0 40 centre>peripheral -20 140 120 20 -40 100 15-PGDH IHC arbitrary units 80 0 peripheral>central 60 40 -20 20 0 -40 centre>peripheral 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 150 100 15-PGDH activity 50 cpm/100 mg peripheral>central 0 -50 1500 2000 -100 1800 1000 pmol/mg 1600 centre>peripheral -150 1400 500 NAD+ 1200 1000 0 800 peripheral>central 600 -500 400 200 -1000 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 -1500 1500 1800 1600 1000 pmol/mg centre>peripheral 1400 500 1200 NADH 0 1000 peripheral>central 800 -500 600 -1000 400 200 -1500 0 -2000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Supplementary Figure 4. Individual paired values from the periphery (blue) and centre (yellow) of 20 CRCLM. The box and whisker plots represent the median, inter-quartile range and range of the absolute difference between central and peripheral tissue values for each tumour. The columns and error bars for 15-PGDH activity are the mean and SD of triplicate values per sample. No IHC scores were derived from central tissue from tumours 14 and 18 in which no tumour cells were evident.

More Related