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Learn about the definitions, causes, and differences between inflammatory and degenerative joint diseases. Discover various treatment options and high-risk medications.
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DEFINITIONS • INFLAMMATORY JOINT DISEASE IS SYSTEMIC, CAUSES STIFFNESS ALL OVER, SWELLING IN JOINTS, PAIN AND FATIGUE • DEGENERATIVE JOINT DISEASE CAUSES PAIN WITH MINIMAL STIFFNESS AND SWELLING AND NO FATIGUE
DIFFERENCE • STIFFNESS IS FAR GREATER IN INFLAMMATORY ARTHRITIS THAN DEGENERATIVE AND SO IS THE FATIGUE/WEAKNESS
ETIOLOGY • INFLAMMATORY IS AUTOIMMUNE (RA, LUPUS), CRYSTAL INDUCED (GOUT), INFECTIOUS, METABOLIC (THYROID,PARATHYROID) • DEGENERATIVE IS GENETIC, END RESULT OF INFLAMMATORY, TRAUMA, AGE...
CASE - 1 80 YEAR OLD WITH MODERATELY SEVERE BACK PAIN AFTER WALKING LESS THAN A MILE, SHE ALSO IS STIFF IN HANDS FOR 45 MIN IN AM
CASE - 2 45 YO WITH GENERALIZED SEVERE PAIN, IN ALL JOINTS AND STIFFNESS THAT LASTS FOR HRS. AFTER TREATMENT HER DEVELOPED INCREASING LEFT HIP PAIN THAT IS PROGRESSIVELY GETTING WORSE.
TREATMENT • HISTORY AND PHYSICAL • LAB • X-RAY/MRI
TREATMENT • PHYSICAL THERAPY • AQUA-THERAPY • FISH OIL/GLUCOSAMINE • EXERCISE • TOPICAL APPLICATIONS
TREATMENT • GLUTEN FREE • MSG, ALFALFA SPROUTS • MEAT, SEA FOOD, BBQ, • COOKED TOMATOES AND EGGPLANTS • ALCOHOL- BEER VERSUS OTHERS
TREATMENT • NSAIDs • DISEASE MODIFYING DRUGS-NON BIOLOGICS • DISEASE MODIFYING DRUGS-BIOLOGICS • RESEARCH
TREATMENT • NON BIOLOGICS EXAMPLES: MTX, SULFA, LEFLUNOMIDE, PLAQUENIL (HCQ), AZATHIOPRINE, CELLCEPT...
TREATMENT • TNF BIOLOGICS: ENBREL, HUMIRA, REMICADE, CIMZIA, SIMPONI, ARIA
TREATMENT • NON-TNF: ORENCIA, RITUXAN, ACTEMRA, BENLYSTA, XELJANZ,
TREATMENT • HIGH RISK MEDS: EDUCATE, SCREEN, VACCINE, HYGENE