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What happens when Meiosis Goes WRONG??

What happens when Meiosis Goes WRONG??. When homologous chromosomes fail to separate it is called “nondisjunction” Abnormal # chromosomes will make their way into gametes This may occur during Meiosis 1 or Meiosis 2 A fetus may be naturally aborted A disorder may occur.

bianca-richmond
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What happens when Meiosis Goes WRONG??

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  1. What happens when Meiosis Goes WRONG??

  2. When homologous chromosomes fail to separate it is called “nondisjunction” • Abnormal # chromosomes will make their way into gametes • This may occur during Meiosis 1 or Meiosis 2 • A fetus may be naturally aborted • A disorder may occur

  3. Trisomy - three of the same number of chromosome

  4. Down Syndrome • Trisomy 21 • Three copies of the 21st chromosome • Mild to severe Mental Retardation • Increased susceptibility to many diseases and higher frequency of some birth defects

  5. When something goes wrong with the division of the sex chromosome….. • Turners- only one X chromosome is inherited • Women are sterile, Sex organs don’t develop at puberty • Kleinefelter’s syndrome • XXY Kleinfelters small testes, man is sterile, female characteristics

  6. Trisomy 18 • Birth defects , increase in infant mortality, developmental delay • Trisomy 13 • Small head, birth size, heart defects, vision and hearing problems, disabilities

  7. Your Job… • Create a Karyotype • Determine the diagnosis • Downsyndrome, Klienfelters, or Turners Syndrome

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