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HOXA9 and its Role in Acute Myeloid Leukemia. Brent Hoffman. HOXA9 is one of the HOX transcription factors regulating Anterior to Posterior patterning in early development. HOXA9 regulates bone marrow stem cell proliferation and cells differentiate as HOXA9 expression decreases.
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HOXA9 and its Role in Acute Myeloid Leukemia Brent Hoffman
HOXA9 is one of the HOX transcription factors regulating Anterior to Posterior patterning in early development
HOXA9 regulates bone marrow stem cell proliferation and cells differentiate as HOXA9 expression decreases
HOXA9 -/- bone marrow cells showed inhibited ability to repopulate in vitro after hematopoietic stress
Acute Myeloid Leukemia is a cancer of the bone marrow affecting white blood cell proliferation and differentiation
Current treatment for AML is divided into two phases: remission induction and post-remission therapy
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