210 likes | 326 Views
Skin Color Monitor. Sarah Offutt, Rachel Mosher, Victoria Vasys BME 301 March 7, 2008. Client: John Webster, Ph.D Department of Biomedical Engineering Advisor: Brenda M. Ogle, Ph.D., M.S. Dept. of Biomedical Engineering. Overview . Problem Statement Background
E N D
Skin Color Monitor Sarah Offutt, Rachel Mosher, Victoria Vasys BME 301 March 7, 2008
Client: John Webster, Ph.D Department of Biomedical Engineering Advisor: Brenda M. Ogle, Ph.D., M.S. Dept. of Biomedical Engineering
Overview • Problem Statement • Background • Physiology of Hot Flashes • Existing Devices • Design Components • Housing Design • Clear Plate • Circuit • Future Work • Questions
Problem Statement The goal is to design a device to monitor skin color changes during hot flashes, which could be used to provide the objective measurement needed for therapeutic drug testing for menopausal women.
Physiology of Hot Flashes • Decreased estrogen levels confuse hypothalamus- body is “too hot” • Due to menopause, medications • Heart pumps faster, blood vessels dilate, blood flow to periphery increases • Skin flushes red • 85% of women experience hot flashes during menopause • Sweating, sleep loss, interruption of daily activities
Existing Devices • Temperature Sensors • Skin conductance measurements • Skin-color-change detectors • We aim to merge the two technologies in order to best detect hot flashes • Longer lasting • Easier use
Last Semester • Blue LED and Phototransistor • Would like to improve on • Specular Reflection elimination • Smaller • Larger color differentiation
PDS Summary • Measurements taken every 10 seconds • 6 x 6 x 1 cm • 50 g • Battery life to last for overnight reading • Comfortable and discreet
Housing Design • Needs: • Aesthetics • Durability • Space for circuitry • Comfort • 3 options • Box • Flat Box • Dome
Skin kept flat Even pressure Needs to be: Transparent Lightweight Safe 3 options NOA61 Acrylic Glass Clear Plate
Circuit • 3 options • Original Design • Parallel Branch Design • Op-Amp Design • Want circuit that will detect the smallest amount of change • Will make biggest difference in quality of project
Circuit 1—Original Few circuit parts Low cost Easy to construct Lowest voltage output Circuit 2—Parallel Few circuit parts Low cost Easy to construct 0-5V output range Circuit Design 1 and 2
Circuit Design 3 • Op-amp • More circuit parts • Increased cost • Harder to construct • Offset resistor • Ranges -5 to 5V
Final Design • Blue LED • Phototransistor • Dome housing design • Acrylic Plate • Op-amp Circuit
Current Work • Specular reflection eliminated • Tested different colors of “skin” • Compared different colors of LEDs • Phototransistor compared with photocell • Housing will be made soon
Future Work • Design Circuit • Finding skin color output range • Setting offset • Testing skin color values with exercise • Making Independent • Print Circuit • -5 to 5V source • Recording device • Implement Housing Design
References • Carpenter, J. S., Azzouz, F., Monahan, P. O., Storniolo, A. M. & Ridner, S. H. (2005). Is sternal skin conductance monitoring a valid measure of hot flash intensity or distress? Menopause, 12(5), 512-9. • Raskin, B. (1987). Hot Flashes. New York: St. Martin’s Press. • Singh, M. & Simpkins, J. W. (Eds.). (2005). The future of hormone therapy : what basic science and clinical studies teach us. New York: New York Academy of Science. • Wearable hot flash monitor (WHFM). Metis Design Corporation. Retrieved February 17, 2008 fromhttp://www.metisdesign.com/biosensors.htm. • Webster, J. G., Bahr, D. E., Shults, M. C., Grady, D. G. & Macer, J. (2006). A miniature sternal skin-attached hot flash recorder. International Federation for Medical and Biological Engineering, 14, 577-580.