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At-Risk Newborn. Twila Brown, PhD, RN. Who Is an At-Risk Infant?. Risk of morbidity or mortality Prenatal and intrapartal risk factors Neonatal factors Gestational age Size Anticipate complications Assessments at birth - Apgar score. High Risk Infant: Overview of Class .
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At-Risk Newborn • Twila Brown, PhD, RN
Who Is an At-Risk Infant? • Risk of morbidity or mortality • Prenatal and intrapartal risk factors • Neonatal factors • Gestational age • Size • Anticipate complications • Assessments at birth - Apgar score
High Risk Infant: Overview of Class • Congenital anomalies • Characteristics and potential problems • Preterm & postterm • Small for gestational age & large for gestational age • General concerns • Thermoregulation • Hypoglycemia • Respiratory distress and complications • Hyperbilirubinemia • Psychosocial neonate & family needs
Congenital Anomalies Diaphragmatic Hernia • Abdominal contents herniate through diaphragm • Respirations are compromised • Signs • Respiratory distress and cyanosis • Barrel shape chest, scaphoid abdomen • Asymmetric chest expansion • Absent breath sounds on effected side • Bowel sounds in chest
Congenital Anomalies: Diaphragmatic Hernia • Interventions • Oxygen • Respiratory support without over inflating • Gastric decompression • Head of bed elevated • Turn to affected side • ECMO • Surgical repair
Congenital Anomalies: Tracheo-Esophageal Fistula • Connection between the trachea and esophagus • Proximal esophagus ends in blind pouch and distal esophagus joined to trachea • Signs • Increased oral secretions • Coughs and choking • Abdominal distention • Not able to pass nasal or oral gastric tube • Struggles with feeding
Congenital Anomalies: Tracheo-Esophageal Fistula • Interventions • Withhold feedings • Elevate head of bed • Suction to blind pouch to decrease aspiration • Surgery
Congenital Anomalies: Neurotubular Defects • Tissue protruding through vertebral column • Meningocele • Meningomyelocele • Impairment • Location and magnitude of defect determines extent of neuro impairment • Sensory impairment follows motor, affects bladder and anal sphincter, contractures and deformities
Congenital Anomalies: Neurotubular Defects • Intervention • Pregnancy -- Folic acid and Alpha fetal protein • Sterile, moist, normal saline dressing • Prevent infection • Decrease trauma • Monitor for changes in fluid and heat loss • Surgical repair, keep prone with legs flexed, no diaper over incision • Long term: hydrocephalus, wheelchair, braces, catheterization
Congenital Anomalies: Gastrocele and Omphalocele • Gastroschisis • Abdominal contents protrude through wall • No sac covering intestines • Omphalocele • Abdominal contents protrude into umbilical cord • Covered by translucent sac • Associated with other anomalies
Congenital Anomalies: Gastrocele and Omphalocele • Interventions • Warm, moist, sterile dressing and plastic wrap • Maintain hydration and temperature • Position supine or side • Gastric decompression • Surgical repair • Complications
Congenital Anomalies: Choanal Atresia • Occlusion at nasopharnyx • Signs • Snorting respirations • Difficulty breathing with feedings • Cyanosis • Interventions • Assess patency of nares • Maintain airway with oral airway • Position with head of bed elevated
Congenital Anomalies: Cleft Lip and Palate • Fissure involving nares, nasal septum, or connecting oral and nasal cavity • Intervention • Feedings with special nipples • Feed upright and burp frequently • Prevent aspiration • Clean mouth after feedings
Congenital Anomalies: Heart Defects • Signs • Cyanosis • Heart murmur • Heart failure • Most common defects • Patent ductus arteriosus • Ventricular septal defect • Coarctation of the aorta • Hypoplastic left heart • Tetralogy of Fallot • Transposition of the great vessels
Substance-abusing Mother: Fetal Alcohol Syndrome • Facial abnormalities • Behaviors • Difficulty establishing respirations • Sleeplessness - Jittery • Hyperalert states - Hyper reflexes • Inconsolable crying - Poor sucking • Irritability - Lethargy
Substance-abusing Mother: Fetal Alcohol Syndrome • Long-term complications • Hypotonic and poor coordination • Mental retardation or normal intelligence • Speech and learning disabilities • Hyperactivity and impulsivity • Growth retardation • Intervention • Treat respiratory distress • Reduce environmental stimulation • Extra feeding time
Substance-abusing Mother: Drug Dependence • Pregnant woman increased risk of • Abruptio placentae, abortion, preterm labor, precipitous labor • Neonate increased risk of • Intrauterine asphyxia • Respiratory problems • Urogenital malformation • Cerebrovascular complications • Low birth weight and head circumference • Drug withdrawal
Substance-abusing Mother: Drug Dependence • Key assessment findings • Tachypnea - Sensitive to stimuli • High-pitched cry - Low birth weight • Jitteriness - Hyperactive Moro reflex • Poor sleeping - Increased reflexes • Irritability - Diarrhea & vomiting • Interventions • Swaddling - Calm environment • Frequent feeding - Medication • Promote bonding
Inborn Error of Metabolism: Phenyleketonuria (PKU) • Condition affects protein metabolism • No enzyme to convert phenylalanine to tyrosine • Affects development of brain and CNS • Mental retardation if untreated • CNS damage minimized if treatment before age 3 months
Inborn Error of Metabolism: Phenyleketonuria (PKU) • Assessment • Positive Guthrie test – 24 hrs after feedings • Failure to thrive - Microcephaly • Vomiting - Hyperactivity • Skin lesions - Irritability • Repetitive motions • Seizures and tremors • Musty odor from skin and urine • Intervention • Low-phenylalanine formula • Teach parents allowed foods in the diet
Inborn Error of Metabolism: Congenital Hypothyroidism • Enzymatic defect, lack of idodine in maternal diet, or maternal drugs can depress thyroid tissue • Causes growth and mental retardation • Assessment • Large tongue = Prolonged jaundice • Umbilical hernia = Poor feeding • Mottled skin = Low-pitch cry • Large fontanelles = Poor weight gain • Hypotonia = Delayed development • Intervention: Monitor thyroid medication
Identification of At-Risk Newborns • Gestational age • Preterm • Post-term • Size of neonate • Small for gestational age • Large for gestational age
Large for Gestational Age • Birth weight at or above the 90th percentile • Etiology • Large parents • Multiparous women • Males larger than female • Assessment findings • Poor muscle tone and motor skills • Difficult to arouse and maintain an alert state
Large for Gestational Age • Complications • Birth trauma – ceohalopelvic disproportion • Asphyxia • Meconium aspiration • Polycythemia • Hypoglycemia
Infant of Diabetic Mother • Severe diabetes associated with vascular complications may have small babies • Mothers with classes A and C may have LGA • High glucose stimulates fetal insulin increase • Complications • Hypoglycemia • Hypocalcemia • Hyperbilirubinemia • Birth trauma
Infant of a Diabetic Mother • Complications • Polycythemia • Respiratory distress syndrome • Congenital birth defects • Interventions • Test blood glucose • Cord blood; q hr X 4; q 4hr for 24 hrs • If blood glucose is < 40 mg/dl • Feeding • IV fluid of 10% dextrose water
Small for Gestational Age • Birth weight at or below the 10th percentile • Intrauterine growth retardation • Deficiency of nutrients through the placenta • Poor nutrition • Smoking or drug use • Pregnancy induced hypertension • Advanced diabetes • Intrauterine infection
Small for Gestational Age • Physical characteristics • Decreased subcutaneous tissue • Loose skin • Thin/dry umbilical cord • Alert for size • Dubowitz changes • Problems • Hypothermia • Hypoglycemia • Asphyxia • Meconium aspiration
Small for Gestational Age • Problems • Hypocalcemia • Feeding difficulties • Polycythemia • Interventions • Support respirations • Provide neutral thermal environment • Provide appropriate nutrition and hydration • Monitor blood glucose levels • Cluster care • Provide skin care
Post-term Infant • Infant born after 42 weeks gestation • Most continue to be well nourished • Postmaturity syndrome • Calcium deposits decrease placenta function • Results in lack of oxygen and nutrients • Physical characteristics • Absent vernix and decreased lanugo • Dry, cracked, parchment-like skin, peeling • Hard, long nails • Abundant scalp hair
Post-term Infant • Physical characteristics • Loose skin • Decreased subcutaneous fat • Problems • Hypothermia • Hypoglycemia • Asphyxia • Meconium aspiration • Polycythemia • Interventions • Supportive
Premature Infant • Born before the 37th week gestation • Physical characteristics • Skin is thin, smooth, shiny, with visible veins • Minimal subcuatneous fat deposits • Lanugo over body • Minimal sole and palm creases • Large head • Ears have soft cartilage • Genitals • Posture is extended • Reflexes absent or weak -- suck, gag
Premature Infant • Problems • Hypothermia • Hypoglycemia • Respiratory distress syndrome • Apnea and bradycardia • Patent ductus arteriosus • Hyperbilirubinemia • Anemia • Intraventricular hemorrhage • Retinopathy of prematurity • Necrotizing entercolitis
Apnea & Bradycardia • Bradycardia: heart rate less than 100 bpm • Apnea: not breathing for > 15 to20 seconds • Causes of apnea • Obstructed airway • Hypothermia or hyperthermia • Hypoglycemia • Sepsis • Respiratory distress
Apnea and Bradycardia • Causes of apnea • Anemia • Hypercapnea • Sepsis • Hypocalcemia • Seizure • Vagal response • Dehydration • CNS depression • Intraventricular hemorrhage
Apnea and Bradycardia • Interventions • Tactile stimulation • Suction airway • Provide oxygen • Provide mechanical ventilation • Correct underlying cause • Administer CNS stimulants • Caffeine or theophylline
Intraventricular hemorrhage • Hemorrhage in the ventricles of the brain • May cause motor deficits • Hydrocephalus • Sight and hearing loss • Causes • Capillary walls vulnerable to hypoxic events • Hypoxia & high CO2 dilates cerebral vessels • Changes in intravascular pressure
Intraventricular hemorrhage • Signs • May be no signs • Bulging fontanel • Signs of intracranial pressure • Interventions • Keep cerebral blood flow constant • Prevent hypoxia • Prevent increased blood pressure • Elevate head of bed
Causes Iron stored late Short life of RBC Blood drawing Hemorrhage Interventions Transfuse Packed red blood cells Iron suppliments and erythopoientin Signs Pallor Tachypnea Dyspnea Tachycardia Activity intolerance Feeding difficulty Anemia
Retinopathy of Prematurity • Progressive disorder of retina vessels • Scar tissue and retina detachment • Causes • Fragile retinal vessels • Fluctuating oxygen administration levels lead to rapid vasodilation and vasoconstriction • Also occurs with hypoxemia, intraventricular hemorrhage, infection, acidosis, exposure to bright lights
Retinopathy of Prematurity • Interventions • Decrease intracranial pressure • Careful O2 administration • Decrease lighting in NICU • Eye exams • May regress spontaneously • Laser/cryosurgery • Vitamin E
Necrotizing entercolitis • Cause • Bowel eschemia during hypoxia • Gas forming bacteria invade damaged cells of intestinal wall • Cells rupture causing air in surface of bowel • Damages bowel wall and causes bleeding • Milk in bowel provides rich media for bacteria growth
Necrotizing entercolitis • Abdominal signs • Pneumotosis in bowel wall • Free air in abdomen if perforated • Distended and shiny abdomen • Gastric retention • Blood in stools • No bowel sounds • Signs of sepsis
Necrotizing entercolitis • Interventions • NPO • Nasal gastric tube for decompression • X-rays to follow deterioration of bowel • Antibiotics • Surgery – resection of damaged portion • Monitor for abdomen distension • Hematest stools • Long-term IV therapy • Decrease O2 consumption
Nutrition for the Preterm • Inability to nipple feed until 35-36 wks • Gag reflex • Suck/swallow/breathe coordination • Tires easily and worsens respiratory distress • Require different composition of formula • Increased metabolic rate • Difficulty consuming calories • Low iron and glycogen stores • Equipment
Nutrition for the Preterm • IV total parenteral nutrition and lipids • Gavage feedings • Calorie requirement • Fluid requirement • High insensible water loss • Urine output • Signs of feeding intolerance
References • Littleton, L.Y., & Engebretson, J.C. (2005). Maternity nursing care. Clifton Park, NY: Thomson Delmar Learning. • Olds, S.B., London, M.L., Ladewig, P.W., & Davidson, M.R. ( 2004). Maternal-newborn nursing & women’s health care (7th ed.). Upper Saddle River, NJ: Prentice Hall. • Silvestri, L.A. (2002). Saunders comprehensive review for NCLEX-RN (2nd ed.). Philadelphia: W.B. Sanders. • Straight A’s in maternal-neonatal nursing. (2004). Philadelphia: Lippincott Williams & Wilkins.