Vaccine Market Size & Share, 2018-2028

1. GLOBAL VACCINE MARKET Focus on Product Type (Next-Generation Vaccine), Route of Administration, Disease Type, 18 Countries Mapping, and Competitive Landscape - Analysis and Forecast, 2018-2028 Key Questions Answered in the Report: • What are the key features of vaccines and how are they promoting vaccines’ incorporation in different clinical applications? How did the global vaccine market evolve and what is its scope in the future? What are the major market drivers, challenges, and opportunities in the global vaccine market? What are the underlying structures resulting in the emerging trends within the vaccine industry? What was the market value of the leading segments and sub-segments of the global vaccine market in 2017? How will each segment of the global vaccine market grow during the forecast period, and what will be the revenue generated by each of the segments by the end of 2028? What are the influencing factors that may affect the market share of the key players? How will the industry evolve during the forecast period 2018-2028? What are the key developmental strategies which are implemented by the key players to sustain in the competitive market? What are the key vaccine type in the global vaccine market? What are the major benefits of each type? How has the market been segmented on the basis of disease type? Which disease type is dominating the global vaccine market, and what is the reason behind its domination? What are the market shares of each of the companies in the global vaccine market, and what are their contributions? Who are the key manufacturers in the global vaccine market, and what are their contributions? What is the scope of each vaccine type, route of administration, and disease type in North America, Europe, Asia-Pacific, Latin America, and Middle East and Africa? What are the key regulatory implications in developed and developing regions for vaccines? What is the growth potential of vaccine in each region, including North America, Europe, Asia-Pacific, Latin America, and Middle East and Africa? Which vaccine type is having the most promising growth and in which disease type? MORE THAN 50+ COMPANIES RESEARCHED ACROSS THE VALUE CHAIN • • • • METICULOUS COMPILATION OF MORE THAN 700 RESEARCH HOURS • • • • • EXCLUSIVE INSIGHTS FROM IN-DEPTH EXPERT INTERVIEWS • • • CONTAINS 12 MARKET DATA TABLES AND 228 FIGURES SPREAD ACROSS 278 PAGES • • • • 1 www.bisresearch.com  sales@bisresearch.com

2. TABLE OF CONTENTS • Different Types and Generation of Vaccines • Vaccines in a Historical Perspective MARKET OVERVIEW REPORT SCOPE AND METHODOLOGY • Assumptions and Limitations for Market Size Calculations • Global Vaccine Market Scenario Report Scope ■ Global Vaccine Market: Research Methodology ■ • Impact Analysis MARKET DYNAMICS • Market Drivers • Market Restraints COMPANY PROFILES • Market Opportunities COMPETITIVE INSIGHTS Abbott Laboratories ■ • Key Strategies and Developments AstraZeneca plc • Market Share Analysis ■ BiondVax Pharmaceuticals Ltd • Industry Attractiveness ■ Bavarian Nordic ■ INDUSTRY INSIGHTS CSL Limited • Regulatory Framework ■ • Regulatory Scenario Daiichi Sankyo Company, Limited ■ • Product Pipeline Analysis Emergent BioSolutions Inc. ■ GLOBAL VACCINE MARKET (BY ROUTE OF ADMINISTRATION) • Intramuscular (IM) Vaccine GlaxoSmithKline plc ■ • Subcutaneous Vaccine Inovio Pharmaceuticals Inc. ■ • Oral Vaccine Johnson & Johnson ■ • Intravenous (IV) Vaccine Merck & Company Inc. ■ • Others GLOBAL VACCINE MARKET (BY TYPE) Madison Vaccines Incorporated ■ • Subunit and Conjugate Vaccine • Inactivated Pfizer, Inc. ■ • Recombinant Sanofi S.A. • Live Attenuated Vaccine ■ • Toxoid Sinovac Biotech Ltd. • Next-generation GLOBAL VACCINE MARKET (BY DISEASE TYPE) ■ Valneva SE ■ VBI Vaccine Inc. • Pneumococcal Disease ■ • DTP • Influenza GLOBAL VACCINE MARKET (BY REGION ) • Cancer • Human Papilloma Virus (HPV) • Meningococcal Disease • Hepatitis VIEW COMPLETE TABLE OF CONTENTS • Measles, Mumps, and Rubella (MMR) • Rotavirus • Varicella • Others • North America • Latin America • Europe • Middle East and Africa • Asia-Pacific 2 www.bisresearch.com  sales@bisresearch.com

3. LIST OF FIGURES 2028 1 Global Vaccine Market Structure 29 Intensity of Competitive Rivalry: Overall Impact, 2015- 2 Impact of Market Drivers and Market Restraints, 2017 2028 and 2028 30 Industry Insights, January 2015-May 2018 3 Global Vaccine Market Snapshot 31 Regulatory Pathway from Preclinical to the Marketing 4 Dominating Segments of Global Vaccine Market, 2017 Authorization and 2028 32 Pipeline Analysis 5 Global Vaccine Market (by Vaccine type), 2017 and 2028 33 Pipeline Analysis According to Clinical Trial Phases 6 Global Vaccine Market (by Route of Administration), 2017 and 2028 34 Global Vaccine Market (by Route of Administration) 7 Global Vaccine Market (by Region), 2017 and 2028 35 Global Vaccine Market (by Route of Administration), 2017-2028 8 Global Vaccine Market (by Region), 2017 and 2028 36 Global Vaccine Market (by Intramuscular), 2017-2028 9 Market Statistics 37 Global Vaccine Market (by Subcutaneous), 2017-2028 10 Market Share Analysis: Global Vaccine Market, 2017 38 Global Vaccine Market (by Oral Vaccine), 2017-2028 11 Opportunity Map Analysis of Next-generation Vaccines 39 Global Vaccine Market (by Intravenous vaccine), 2017- 12 Classification of Global Vaccine Market 2028 13 Different Types and Generation of Vaccines 40 Global Vaccine Market (by Others), 2017-2028 14 Components of a Vaccine 41 Global Vaccine Market (by Type) 15 Evolution of Vaccines against Diseases 42 Global Vaccine Market (by Type), 2017-2028 16 Global Vaccine Market, 2017-2028 43 Global Vaccine Market (by Subunit and Conjugate), 17 Market Dynamics of Global Vaccine Market 2017-2028 18 Competitive Landscape, January 2015-September 2018 44 Global Vaccine Market (by Live Attenuated), 2017-2028 19 Share of Key Developments and Strategies, January 45 Global Vaccine Market (by Inactivated), 2017-2028 2015-September 2018 46 Global Vaccine Market (by Recombinant), 2017-2028 20 Product Launches Share (by Companies), January 2015- 47 Global Vaccine Market (by Toxoid), 2017-2028 September 2018 48 Global Vaccine Market (by Next-Generation), 2021-2028 21 Joint Ventures, Partnerships, and Collaborations Share (by Companies), January 2015-September 2018 49 Global Vaccine Market (by Disease Type) 22 Others Share (by Companies), January 2015-September 50 Global Vaccine Market (by Pneumococcal Disease), 2018 2017-2028 23 Market Share Analysis: Global Vaccine Market, 2016 and 51 Global Pneumococcal Disease Vaccine Market (by 2017 Region), 2017-2028 24 Porter’s Five Forces Analysis 52 Global Vaccine Market (by DTP), 2017-2018 25 Bargaining Power of Suppliers: Overall Impact, 2015- 53 Global DTP Disease Vaccine Market (by Region), 2017- 2028 2028 26 Bargaining Power of Buyers: Overall Impact, 2015-2028 54 Global Vaccine Market (by Influenza), 2017-2028 27 Threat of New Entrant: Overall Impact, 2015-2028 55 Global Influenza Vaccine Market (by Region), 2017-2028 28 Threat of Substitute Products: Overall Impact, 2014- 56 Global Vaccine Market (by Cancer), 2017-2028 3 www.bisresearch.com  sales@bisresearch.com

4. LIST OF FIGURES 88 Spain Vaccine Market, 2017-2028 57 Global Cancer Vaccine Market (by Region), 2017-2028 89 Italy Vaccine Market, 2017-2028 58 Global Vaccine Market (by HPV), 2017-2028 90 Switzerland Vaccine Market, 2017-2028 59 Global HPV Vaccine Market (by Region), 2017-2028 91 Rest-of-Europe Vaccine Market, 2017-2028 60 Global Vaccine Market (by Meningococcal Disease), 2017-2028 92 APAC Vaccine Market, 2017-2028 61 Global Meningococcal Disease Vaccine Market (by 93 APAC: Market Dynamics Region), 2017-2028 94 APAC Vaccine Market (by Country), 2017-2028 62 Global Vaccine Market (by Hepatitis), 2017-2028 95 APAC Vaccine Market (by Vaccine Type), 2017-2028 63 Global Hepatitis Disease Vaccine Market (by Region), 96 APAC Vaccine Market (by Route of Administration), 2017-2028 2017-2028 64 Global Vaccine Market (by MMR), 2017-2028 97 China Vaccine Market, 2017-2028 65 Global MMR Vaccine Market (by Region), 2017-2028 98 India Vaccine Market, 2017-2028 66 Global Vaccine Market (by Rotavirus), 2017-2028 99 Japan Vaccine Market, 2017-2028 67 Global Rotavirus Vaccine Market (by Region), 2017- 100 Australia Vaccine Market, 2017-2028 2028 101 South Korea Vaccine Market, 2017-2028 68 Global Vaccine Market (by Varicella), 2017-2028 102 Rest-of-APAC Vaccine Market, 2017-2028 69 Global Varicella Vaccine Market (by Region), 2017-2028 103 Latin America Vaccine Market, 2017-2028 70 Global Vaccine Market (by Others), 2017-2028 104 Latin America: Market Dynamics 71 Global Vaccine Market (by Region), 2017 and 2028 105 Latin America Vaccine Market (by Country), 2017-2028 72 Global Vaccine Market (by Vaccine Market), 2017-2028 106 Latin America Vaccine Market (by Vaccine Type), 2017- 73 North America Vaccine Market, 2017-2028 2028 74 North America: Market Dynamics 107 Latin America Vaccine Market (by Route of 75 North America Vaccine Market (by Country), 2017- Administration), 2017-2028 2028 108 Brazil Vaccine Market, 2017-2028 76 North America Vaccine Market (by Vaccine Type), 2017- 109 Mexico Vaccine Market, 2017-2028 2028 110 Rest-of-Latin America Vaccine Market, 2017-2028 77 North America Vaccine Market (by Route of 111 Middle East and Africa Vaccine Market, 2017-2028 Administration), 2017-2028 112 Middle East and Africa: Market Dynamics 78 U.S. Vaccine Market, 2017-2028 113 Middle East and Africa Vaccine Market (by Country), 79 Canada Vaccine Market, 2017-2028 2017-2028 80 Europe Vaccine Market, 2017-2028 114 Middle East and Africa Vaccine Market (by Vaccine 81 Europe: Market Dynamics Type), 2017-2028 82 Europe Vaccine Market (by Country), 2017-2028 115 Middle East and Africa Vaccine Market (by Route of 83 Europe Vaccine Market (by Vaccine Type), 2017-2028 Administration), 2017-2028 84 Europe Vaccine Market (by Route of Administration), 116 GCC Vaccine Market, 2017-2028 2017-2028 117 South Africa Vaccine Market, 2017-2028 85 Germany Vaccine Market, 2017-2028 118 Rest-of- Middle East and Africa Vaccine Market, 2017- 86 France Vaccine Market, 2017-2028 2028 87 U.K. Vaccine Market, 2017-2028 4 www.bisresearch.com  sales@bisresearch.com

5. LIST OF FIGURES 149 Daiichi Sankyo Company, Limited: Revenue (by 119 Share of Key Company Profiled Business Segment), 2015-2017 120 Abbott India Ltd. (Subsidiary of Abbott Laboratories): 150 Daiichi Sankyo Company, Limited: Revenue (by Product Offerings for Global Vaccine Market Region), 2015-2017 121 Abbott Laboratories: Overall Financials, 2015-2017 151 Daiichi Sankyo Company, Limited: R&D Expense, 2015- 122 Abbott Laboratories: Revenue (by Business Segment), 2017 2015-2017 152 Daiichi Sankyo Company, Limited: Revenue Forecast, 123 Abbott Laboratories: Revenue (by Region), 2015-2017 2015-2020 124 Abbott Laboratories: R&D Expense, 2015-2017 153 Daiichi Sankyo Company, Limited: SWOT Analysis 125 Abbott Laboratories: Revenue Forecast, 2015-2020 154 Emergent BioSolutions Inc.: Product Offerings for 126 Abbott Laboratories: SWOT Analysis Global Vaccine Market 127 AstraZeneca plc: Product Offerings for Global Vaccine 155 Emergent BioSolutions Inc.: Overall Financials, 2015- Market 2017 128 AstraZeneca plc: Overall Financials, 2015-2017 156 Emergent BioSolutions Inc.: Revenue (by Region), 129 AstraZeneca plc: Revenue (by Region), 2015-2017 2015-2017 130 AstraZeneca plc: R&D Expense, 2015-2017 157 Emergent BioSolutions Inc.: R&D Expense, 2015-2017 131 AstraZeneca PLC: SWOT Analysis 158 Emergent BioSolution Inc.: Revenue Forecast, 2015- 132 BiondVax Pharmaceuticals Ltd.: Overall Financials, 2020 2015-2017 159 Emergent BioSolutions Inc.: SWOT Analysis 133 BiondVax Pharmaceuticals Ltd.: R&D Expense, 2015- 160 GlaxoSmithKline plc: Product Offerings for Global 2017 Vaccine Market 134 BiondVax Pharmaceuticals Ltd.: SWOT Analysis 161 GlaxoSmithKline plc: Overall Financials, 2015-2017 135 Bavarian Nordic: Overall Financials, 2015-2017 162 GlaxoSmithKline plc: Revenue (by Business Segment), 136 Bavarian Nordic: Revenue (by Region), 2015-2017 2015-2017 137 Bavarian Nordic: R&D Expense, 2015-2017 163 GlaxoSmithKline plc: Revenue (by Region), 2015-2017 138 Bavarian Nordic: Revenue Forecast, 2015-2020 164 GlaxoSmithKline plc: R&D Expense, 2015-2017 139 Bavarian Nordic: SWOT Analysis 165 GlaxoSmithKline plc: Revenue Forecast, 2015-2020 140 CSL Limited: Product Offerings for Global Vaccine 166 GlaxoSmithKline plc: SWOT Analysis Market 167 Product Offerings 141 CSL Limited: Overall Financials, 2015-2017 168 Inovio Pharmaceuticals Inc.: Overall Financials, 2015- 142 CSL Limited: Revenue (by Business Segment), 2015- 2017 2017 169 Inovio Pharmaceuticals Inc..: R&D Expense, 2015-2017 143 CSL Limited: Revenue (by Region), 2015-2017 170 Inovio pharmaceuticals Inc.: Revenue Forecast, 2015- 144 CSL Limited: R&D Expense, 2015-2017 2020 145 CSL Limited: Revenue Forecast, 2015-2020 171 Inovio Pharmaceutical Inc.: SWOT Analysis 146 CSL Limited: SWOT Analysis 172 Johnson & Johnson: Product Offerings for Global 147 Daiichi Sankyo Company, Limited: Product Offerings for Vaccine Market Global Vaccine Market 173 Johnson & Johnson: Overall Financials, 2015-2017 148 Daiichi Sankyo Company, Limited: Overall Financials, 174 Johnson & Johnson: Revenue (by Business Segment), 2015-2017 2015-2017 5 www.bisresearch.com  sales@bisresearch.com

6. LIST OF FIGURES 207 Sinovac Biotech Ltd.: SWOT Analysis 175 Johnson & Johnson: Revenue (by Region), 2015-2017 208 Valneva SE: Product Offerings for Global Vaccine 176 Johnson & Johnson: R&D Expense, 2015-2017 Market 177 Johnson & Johnson: Revenue Forecast, 2015-2020 209 Valneva SE.: Overall Financials, 2015-2017 178 Johnson & Johnson: SWOT Analysis 210 Valneva SE: Revenue (by Business Segment), 2015- 179 Merck & Co. Inc.: Product Offerings for Global Vaccine 2017 Market 211 Valneva SE: Revenue (by Region), 2015 & 2017 180 Merck & Co: Overall Financials, 2015-2017 212 Valneva SE: R&D Expense, 2015-2017 181 Merck & Co. Inc..: Revenue (by Business Segment), 213 Valneva SE: Revenue Forecast, 2015-2020 2015-2017 214 Valneva SE.: SWOT Analysis 182 Merck & Co. Inc..: Revenue (by Region), 2015-2017 215 VBI Vaccine Inc.: Product Offerings for Global Vaccine 183 Merck & Co. Inc..: R&D Expense, 2015-2017 Market 184 Merck & Co. Inc..: Revenue Forecast, 2015-2020 216 VBI Vaccine Inc.: Overall Financials, 2015-2017 185 Merck & Co. Inc.: SWOT Analysis 217 VBI Vaccine Inc. Revenue (by Region) 2015-2017 186 Madison Vaccines Incorporated: SWOT Analysis 218 VBI Vaccine Inc.: R&D Expense, 2015-2017 187 Pfizer, Inc.: Product Offerings for Global Vaccine Market 219 VBI Vaccine Inc.: SWOT Analysis 188 Pfizer, Inc.: Overall Financials, 2015-2017 220 Global Vaccine Market: Market Segmentation 189 Pfizer, Inc.: Revenue (by Business Segment) 2015- 221 Global Vaccine Market Segmentation 2017 222 Primary Research 190 Pfizer, Inc.: Revenue (by Region) 2015- 2017 223 Secondary Research 191 Pfizer, Inc.: R&D Expense, 2015-2017 224 Data Triangulation 192 Pfizer, Inc.: Revenue Forecast, 2015-2020 225 Top-down Approach (Segment-wise Analysis) 193 Pfizer, Inc.: SWOT Analysis 226 Bottom-up Approach (Segment-wise Analysis) 194 Sanofi S.A.: Product Offerings for Global Vaccine Market 227 Assumptions and Limitations 195 Pipeline Products 228 Considered Factors for Data Prediction and Modelling 196 Sanofi S.A.: Overall Financials, 2015-2017 197 Sanofi S.A..: Revenue (by Business Segment), 2015- 2017 198 Sanofi S.A.: Revenue (by Region), 2015-2017 199 Sanofi S.A.: R&D Expense, 2015-2017 200 Sanofi S.A..: Revenue Forecast, 2015-2020 201 Sanofi S.A..: SWOT Analysis 202 Sinovac Biotech Ltd.: Product Offerings for Global Vaccine Market 203 Sinovac Biotech Ltd..: Overall Financials, 2015-2017 204 Sinovac: Revenue (by Region), 2015-2017 205 Sinovac Biotech Ltd.: R&D Expense, 2015-2017 206 Sinovac Biotech Ltd.: Revenue Forecast, 2015-2020 6 www.bisresearch.com  sales@bisresearch.com

7. LIST OF TABLES 1 Impact Analysis 2 Vaccination Coverage (by Vaccine and WHO Region) - Worldwide, 2016 3 Number of Mergers and Acquisitions (by Each Company), January 2015-September 2018 4 Number of Business Expansion (by Each Company), January 2015-September 2018 5 The European Medicines Agency’s Scientific Guidelines on Vaccines 6 Regulatory Scenario Across the World 7 Global Vaccine Market (by Disease Type), 2017-2028 8 North America Vaccine Market (by Disease Type), 2017-2028 9 Europe Vaccine Market (by Disease Type), 2017-2028 ($Billion) 10 APAC Vaccine Market (by Disease Type), 2017-2028 ($Billion) 11 Latin America Vaccine Market (by Disease Type), 2017- 2028 ($Billion) 12 Middle East and Africa Vaccine Market (by Disease Type), 2017-2028 ($Billion) 7 www.bisresearch.com  sales@bisresearch.com

8. 1 The Research Scope & Methodology 1.1 Scope of the Report The report comprises an in-depth study of the vaccine market, including a thorough analysis of the products and services across different regions. The study also presents a detailed analysis of the market trends and the market size for the period 2017 to 2028 wherein 2017 is the base year and the years from 2018 to 2028 constitute the forecast period. The report covers all the prevalent trends which are expected to play a major role in the growth of the market over the forecast period. It also highlights various drivers, restraints, and opportunities which are expected to influence the market’s growth during the forecast period. The scope of this report is focused on the global vaccine market, products, their market dynamics, growth prospect mapping, SWOT analysis, Porter’s Five Forces, and country-wise analysis. The study provides a holistic perspective on the market growth in terms of revenue estimates across different geographies which include North America, Europe, Asia-Pacific (APAC), Latin America and Middle East, and Rest-of-the-World (RoW). The report provides cross-sectional analysis of the global vaccine market in terms of market estimates and projections, for different disease type across different region. Further, the region has been sub-segmented on the basis of vaccine type, disease type and route of administration. The regions have been further segmented to cover the in-depth country level analysis. The North American region has been segmented into the U.S., and Canada. Similarly, Europe has been further segmented into the U.K., Germany, France, Italy, Spain, Switzerland, and Rest-of-Europe. Asia- Pacific has been segmented into China, Japan, Australia, India, South Korea, and Rest-of-Asia-Pacific; Middle East and Africa has been segmented to Gulf Cooperation Council (GCC) and South Africa; and Latin America has been segmented to Mexico and Brazil. The revenue estimates for these countries has also been included in the report. 1.2 BIS Research Market Research Methodology The research methodology design adopted for this specific study includes a mix of data collected from primary and secondary sources. Both primary sources (in-house experts, industry leaders, and market players) and secondary sources (a host of paid and unpaid databases) along with analytical tools have been used exhaustively to build the forecast and predictive models. 8 www.bisresearch.com  sales@bisresearch.com

9. Figure 1 BIS Research Market Research Methodology RESEARCH APPROACH SECONDARY RESEARCH PRIMARY RESEARCH DATA SOURCES Company Information  OneSource Business Browser  Hoover’s  10K Wizard  Bloomberg  The Wall Street Journal  Factiva 1. DATABASE FOR KEY INDUSTRY PARTICIPANTS (DKIP) PREPARATION STUDYING THE MARKET STRUCTURE The primary sources from the supplyside include industry experts, such as CEOs, vice presidents, marketingdirectors, technologyand innovation directors, and related keyexecutives from various vendors providing technology solutions, associated service providers, and system integrators operatingin the targeted regions. E.g. CEOs and VPs/Directors (New Product Developmentand Operations) Mainly used to obtain key information about the industry’s value chain and the total pool of key players Subject Information  Scientific Journals  Press Releases  White Paper  Government Stats Centers  Non-Profit Associations  Public and Private Databases IDENTIFY MARKET, TECHNOLOGY, AND COMPETITOR TRENDS 2. DISCUSSION GUIDE PREPARATION Understand market classification and segmentation according to industry trends to the bottom-most level, regional markets, and key developments from both market-and technology-oriented perspectives Adetailed questionnaire is shared with the primaryrespondent coveringall the aspects related to the report topic. Regulation Information • CDC • WHO • FDA • EMA 3. SCHEDULING AN APPOINTMENT Appointments are scheduled with CEO and VP/Director – healthcare companies. The discussion guide is then shared with theprimaryrespondent prior to thecall. INTEGRATE INFORMATION Integrate information within relevant documents to form the launchpad for primary research 4. CALL EXECUTION Aroundtable discussion is held with the KeyIndustryPlayers (KIP)with the aim to gather first-hand information about the technology, recent developments in the technology, and future outlook - growth or decline. VENDORS CONSULTANT RESELLERS 5. DOCUMENTATION POTENTIAL RESPONDENTS The interview is recorded and the information gathered through the primaryresearch is put on the drawingboard with theinformation collected through thesecondaryresearch. Managed Service Providers (MSPs) END USER BIS Research Analysis Primary Data Sources The key data points taken from the primary sources include: • Validation and Triangulation of all the numbers and graphs • Validation of report segmentation and key qualitative findings • Understanding the competitive landscape • Understanding and considering the factors for market dynamics of various market segments and sub- segments • Validation of impact analysis of macro and micro factors in different countries • Percentage split of individual markets for geographical analysis Secondary Data Sources The research study involves the usage of extensive secondary sources such as databases, company websites, and annual reports, among others. 9 www.bisresearch.com  sales@bisresearch.com

10. The following figure exhibits key secondary data sources considered in this report: Figure 2 Secondary Data Sources COMPANY SOURCES STOCK ANALYST WEBSITES Annual reports Press Releases SEC Filings Investor presentations Financial Disclosures Seeking Alpha Yahoo Finance Wiki Finance The Wall Street Journal SECONDARY DATA SOURCES GOVERNMENT AND REGULATORY SOURCES PUBLIC AND PRIVATE DATABASES Centers for Disease Control Prevention (CDC) The World Health Organization (WHO) The National Health Services (NHS) The National Center for Biotechnology Information (NCBI) The Food & Drug Administration of United States (U.S. FDA) Medline PubMed National Library of Medicine ProQuest CMS Datasets Medicare Beneficiaries Database BIS Research Analysis The key data points taken from the secondary sources include: • Segmentation breakups, split-ups, and percentage shares • Data for market value • Key industry trends of the top players of the market • Qualitative insights into various aspects of the market, key trends, and emerging areas of innovation • Quantitative data for mathematical and statistical calculations 10 www.bisresearch.com  sales@bisresearch.com

11. The following figure exhibits data triangulation considered in this study: Figure 3 Data Triangulation PRIMARY SOURCES SECONDARY SOURCES INTERVIEWS WITH: • Senior management of the leading vaccine companies market • Vice Presidents of probiotics companies • Top scientists and professors from universities • R&D managers and product managers of the leading players in the industry • Top research organizations conducting research focused upon emerging technological advancements SEC Filings of the leading market players • Company websites and detailed study of their product portfolio • Annual reports, investor presentations of the key players in the market • Magazines, journals, white papers, press releases, news articles etc. • INFORMATION SOURCED SUPPLY SIDE National Institute of Health(NIH), Centerfor Disease Control (CDC), Food Drug and Administration(FDA), Food and Agriculture Organization of the United Nations (FAO), World Health Organization (WHO), European Food Safety Authority (EFSA), PubMed, European Business Directory, and The Economist Intelligence Unit (EIU), among others • DATA TRIANGULATION PRIMARY SOURCE SECONDARY SOURCE Annual Reports, SEC Filings, Investor Presentations, Websites, and Press Releases of top players, News Articles, Journals, and Paid Databases INFORMATION SOURCED Opportunities/ Challenges Market Size and Market Share Key Players Competitive Landscape Geographical Analysis Market Trends Influencing Factors Market Estimates BIS Research Analysis REQUEST FOR SAMPLE 11 www.bisresearch.com  sales@bisresearch.com