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Featured Article :. Severe Hypoglycemia and Mortality After Cardiovascular Events for Type 1 Diabetic Patients in Sweden. Tom W.C. Lung, Dennis Petrie, William H. Herman, Andrew J. Palmer, Ann-Marie Svensson, Bjorn Eliasson, and Philip M. Clarke. Diabetes Care Volume 37: 2974-2981

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Featured Article :

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  1. Featured Article: Severe Hypoglycemia and Mortality After Cardiovascular Events for Type 1 Diabetic Patients in Sweden Tom W.C. Lung, Dennis Petrie, William H. Herman, Andrew J. Palmer, Ann-Marie Svensson, Bjorn Eliasson, and Philip M. Clarke Diabetes Care Volume 37: 2974-2981 November, 2014

  2. STUDY OBJECTIVE • To examine whether previous severe hypoglycemic events were associated with the risk of all-cause mortality after major cardiovascular events in type 1 patients Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  3. STUDY DESIGN AND METHODS • Data were from the Swedish National Diabetes Register • Patients included those with type 1 diabetes who visited a clinic during 2002–2010 and experienced a major cardiovascular complication after the visit • Two-part model was estimated for all-cause mortality after a cardiovascular event: 1. Logistic regression for death within the first month 2. Cox proportional hazards model conditional on 1-month survival • 5-year cumulative mortality risk was estimated from the models for patients with and without prior diabetes complications Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  4. RESULTS • 1,839 patients experienced major cardiovascular events • 403 had previously experienced severe hypoglycemic events • 703 died within our study period • A prior hypoglycemic event was associated with a significant increase in mortality after a cardiovascular event • Patients with prior hypoglycemia had an estimated 5-year cumulative mortality risk of 52.4 and 39.8% for myocardial infarction and stroke, respectively Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  5. Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  6. Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  7. Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  8. CONCLUSIONS • Patients with type 1 diabetes in Sweden with prior severe hypoglycemic events have increased risk of mortality after a cardiovascular event Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

  9. Lung T. W.C. et al. Diabetes Care 2014;37:2974-2981

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