1 / 3

MOPDB0103

MOPDB0103. Longitudinal Study of Bone Mineral Density and Vitamin D Levels Among Perinatally HIV-infected Thai Adolescents Receiving Long Term Antiretroviral Therapy.

bliss
Download Presentation

MOPDB0103

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. MOPDB0103 Longitudinal Study of Bone Mineral Density and Vitamin D Levels Among Perinatally HIV-infected Thai Adolescents Receiving Long Term Antiretroviral Therapy A 2 times DXA study at 12-24 months apart with life style modification education, without calcium and vitamin D supplement SurapongTanchaweng, MD aThanyaweePuthanakit, MD b,c, RachaneeSaksawad, MD a, ChantapatBrukesawan MD a, Alan Maleesatharn, MBAa, KulkanyaChokephaibulkit, MD a,* a Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 10700. b Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 10330. c HIV-NAT/Thai Red Cross AIDS Research, 104 Ratchadamri Road, Pathumwan, Bangkok Thailand 10330.

  2. Results • 46 adolescents with median age 14.5 yrs at 1st measurement • Receiving TDF 41.3% and 54.3% at 1st and 2nd measurement respectively • Intervention : life style modification education, no calcium and vitamin D • supplement N(%) P=0.001 P<0.001 P<0.001 P=0.013 Being male was associated with worsening of BMD (OR 4.8, 95%CI 1.1-20.7) p=0.022

  3. Conclusions • We found worsening of BMD over 12-24 months in Thai HIV-infected adolescents. • Educational counseling improve vitamin D levels, but not BMD. • Decrease BMD over 12-24 months was associated with being male but not associated with receiving of PIs, NNRTI or TDF. Acknowledgements We would like to thank all our patients the TREAT Asia/amfAR, All the expert assistance provided by the Division of Pediatric endocrinology and Division of Infectious Diseases Department of Pediatrics Faculty of Medicine Siriraj Hospital MahidolUniversity, Thailand

More Related