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Platform Technologies for Medical Devices: Case of the Brain-Machine Interface

Peter Konrad, MD PhD Director, Functional Neurosurgery Vanderbilt University. Platform Technologies for Medical Devices: Case of the Brain-Machine Interface. Disclosures. Consulting: Medtronic Neurological; FHC Inc. Fiduciary Position: CMO – Neurotargeting LLC

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Platform Technologies for Medical Devices: Case of the Brain-Machine Interface

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  1. Peter Konrad, MD PhD Director, Functional Neurosurgery Vanderbilt University Platform Technologies for Medical Devices:Case of the Brain-Machine Interface

  2. Disclosures Consulting: Medtronic Neurological; FHC Inc. Fiduciary Position: CMO – Neurotargeting LLC Will not discuss off label use of approved FDA products

  3. Device Platform Technology ? Neurological Device Platform Technology

  4. Emergence of Extrinsic Neurally Controlled Systems • Goals: Restore Useful Sensory-Motor Control • Methods: • Extract Control Information • Insert Sensory Feedback • Information Processing Stroke Motor Signal Extraction SCI Sensory Signal Insertion ALS Amputation

  5. Cortically Based Interface

  6. Beta Band (20-30Hz) activity following Go Cue in primary motor cortex Hochberg et al. Nature 442: 164-171, 2006

  7. Subcortical Based Interface: Motor Signal Extraction

  8. Sub-Cortical Based Interface: Sensory Signal Insertion

  9. Sub-Cortical Based Interface: Sensory Signal Insertion

  10. BMI Output: Where Should It Go?

  11. BMI Output: Where Should It Go?

  12. Functional Neuromuscular Stimulation:Output Interface Already Put in Practice Examine alternative user command interfaces -- based on facial and neck EMG signals, as well as head orientation. Courtesy: Dr. Hunter Peckham

  13. Intramuscular electrode Functional Neuromuscular Stimulation:Output Interface Already Put in Practice EMG based Control – hand grasp opening: brachioradialis | closing: trapezius EMG Courtesy: Dr. Hunter Peckham

  14. Future of Device Platform Technologies

  15. Future of Device Platform Technologies • Approved: signal insertion (+ a few signal extraction) implants • ? Signal processing needs • ? Body LAN • Can we take cues from computer / communications industry? Stroke Motor Signal Extraction SCI Sensory Signal Insertion ALS Amputation

  16. Device Platform Technology Neurological Device Platform Technology

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