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RESPOSTA METABÓLICA AO TRAUMA

RESPOSTA METABÓLICA AO TRAUMA. Prof. Wolnei Caumo Serviço de Dor e Medicina Paliativa do HCPA Departamento de Farmacologia - ICSB-UFRGS Departamento de Cirurgia - FAMED/UFRGS. EXISTEM EVIDÊNCIAS DE MEDIDAS TERAPÊUTICAS USADAS NO MANEJO DA RESPOSTA ENDÓCRINA AO TRAUMA?.

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RESPOSTA METABÓLICA AO TRAUMA

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  1. RESPOSTA METABÓLICA AO TRAUMA Prof. Wolnei Caumo Serviço de Dor e Medicina Paliativa do HCPA Departamento de Farmacologia - ICSB-UFRGS Departamento de Cirurgia - FAMED/UFRGS

  2. EXISTEM EVIDÊNCIAS DE MEDIDAS TERAPÊUTICAS USADAS NO MANEJO DA RESPOSTA ENDÓCRINA AO TRAUMA?

  3. Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults: A Systematic Review Djillali Annane; Eric Bellissant; Pierre-Edouard Bollaert; et al. JAMA. 2009;301(22):2362-2375 (doi:10.1001/jama.2009.815 Mortalidade em 28 d - (RR= 0.84 (IC 95%, 0.72-0.97) Reversão do choque RR= 1.12 (IC 95%; 1.02-1.23) Tempo médio de permanecia no CTI 4.49 d (IC 95%; –7.04 to –1.94) (RR, 0.84; 95% CI, 0.72- 0.97; P=.02).

  4. IMPACTO DE INTERVENÇÕES NA MORBI-MORTALIDADE Hypothermia for traumatic head injury. Efeito na mortalidade OR = 0.84 (IC 95%; 0.67 to 1.05) Cochrane Database Syst Rev. 2009 Apr 15;(2):CD001048. Sydenham E, Roberts I, Alderson P. Effect of epidural analgesia in patients with traumatic rib fractures: a systematic review and meta-analysis of randomized controlled trials Mortalidade OR=1.6 (IC 95%, 0.3, 9.3, 3) Tempo de permanência no CTI (DMP) -3.7 d (IC 95% -11.4 a 4) Tempo de permanência hospitalar (DMP) -6.7 (IC 95% -19.8 a 6.4) Tempo de ventilação mecânica (DMP) -7.5 (IC 95%; -16.3 a 1.2) Tempo de ventilação mecânica (DMP) – BP torácico – analgesia com anestésico local (DMP) -4.2 (IC 95%; -5.5, -2.9) Can J Anaesth. 2009 Mar;56(3):230-42. Epub 2009 Feb 11. Carrier FM, Turgeon AF, Nicole PC, Trépanier CA, Fergusson DA, Thauvette D, Lessard MR.

  5. IMPACTO DE INTERVENÇÕES NA MORBI-MORTALIDADE Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis RR mortalidade 1.5 Aumento no escore da Escala de Glasgow Tempo de permanecia no CTI RR=2,8 Tempo de permanência hospitalar RR=3,2 Greer DM, Funk SE, Reaven NL, Ouzounelli M, Uman GC Stroke. 2008 Nov;39(11):3029-35. Epub 2008 Aug 21. . Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults: A Systematic Review Mortalidade em 28 d - (RR= 0.84 (IC 95%, 0.72-0.97) Reversão do choque RR= 1.12 (IC 95%; 1.02-1.23) Tempo médio de permanecia no CTI 4.49 d (IC 95%; –7.04 to –1.94) Djillali Annane; Eric Bellissant; Pierre-Edouard Bollaert; et al. JAMA. 2009;301(22):2362-2375 (doi:10.1001/jama.2009.815

  6. Towards Understanding Tight Glycemic Control in the ICU: A Systematic Review and Meta-analysis Mortalidade em 28 d - OR 0.95 (IC 95%; 0.87-1.05) - NPT Chest. 2009 Dec 16. [Epub ahead of print] Marik PE, Preiser JC. IMPACTO DE INTERVENÇÕES NA MORBI-MORTALIDADE A systematic review of heparin to treat burn injury Mortalidade 0.32 (IC 95%; 0.18-0.57) J Burn Care Res. 2007 Nov-Dec;28(6):794-804.. Oremus M, Hanson MD, Whitlock R, Young E, Archer C, Dal Cin A, Gupta A, Raina P.

  7. Immunonutrition in critically ill patients: a systematic review and analysis of the literature Arginina, arginina e glutamina, arginina e óleo de peixe Infecção OR 0.63 (IC 95%; 0.47-0.86) Nos que receberam óleo de peixe Mortalidade OR 0.42, 95% CI 0.26-0.68 e infecção (OR 0.42, 95% CI 0.26-0.68; OR 0.45 (IC 95%, 0.25-0.79) Tempo de permeância hospitalar -6.28 d (IC 95% -9.92 a -2.64) Intensive Care Med. 2008 Nov;34(11):1980-90. Epub 2008 Jul 15. Marik PE, Zaloga GP.

  8. Interventions for preventing critical illness polyneuropathy and critical illness myopathy NEUROPATIA/ MIOPATA - RR - 0.65 (CI 95%, 0.55 - 0.78) TEMPO DE VENTILAÇÃO MECÂNICA, TMEPO DE PERMANÂNCIA NO CTI, MORTALIDADE EM 180 DIAS Cochrane Database Syst Rev. 2009 Jan 21;(1):CD006832.. Hermans G, De Jonghe B, Bruyninckx F, Van den Berghe G.

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