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ROBERT C ATKINS BELLAGIO, MARCH 2004

DEVELOPMENT OF STRATEGIES FOR PREVENTION OF CHRONIC KIDNEY DISEASE RELEVENT TO DIFFERENT REGIONS AND COUNTRIES. ROBERT C ATKINS BELLAGIO, MARCH 2004. Eur: 317,000. China: 30,000. USA: 283,000. Japan: 167,000. India: 20.000. Latin Am: 82,000. AUS/NZL: 11,000. World-ESRD (1996).

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ROBERT C ATKINS BELLAGIO, MARCH 2004

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  1. DEVELOPMENT OF STRATEGIES FOR PREVENTION OF CHRONIC KIDNEY DISEASE RELEVENT TO DIFFERENT REGIONS AND COUNTRIES ROBERT C ATKINS BELLAGIO, MARCH 2004

  2. Eur: 317,000 China: 30,000 USA: 283,000 Japan: 167,000 India: 20.000 Latin Am: 82,000 AUS/NZL: 11,000 World-ESRD (1996) Prevalence Incidence 1,000,000 220,000 DIALYSIS PATIENTS WORLD-WIDE (1996) Schena, Kidney Int (Suppl 74), 2000

  3. Incidence of Diabetes in E.S.R.F Australia 1980 - 2000 Number of Diabetics Number of New Patients Year of Entry

  4. CAUSES OF ESRD IN THE USA 140 Diabetes 120 100 80 Hypertension Incidence rates (x million population) 60 Glomerulonephritis 40 20 Cystic kidney 0 1990 1992 1994 1996 1998 USRDS, 2000 • Diabetes and hypertension are the main causes for ESRD in the USA • The proportion of ESRD patients with diabetic nephropathy is higher in the USA than in Europe. However, diabetic nephropathy is the most rapidly growing cause of ESRD in European countries

  5. AUSDIAB RESULTS • 7.2% with diabetes (3.6% known and 3.6% newly diagnosed) • 16.1% with impaired glucose metabolism • 60% overweight or obese • 61.3% with high cholesterol (7.3% on treatment) • 29% with high blood pressure (14% on treatment)

  6. PREVALENCE OF RENAL ABNORMALITIES 1. Haematuria >10x106/L 4.6% 2. Proteinuria 2.4% UP:UC>0.2 mg/mg3. Renal Impairment 11.2% calculated GFR <60 mls/min No abnormality 82% At least one abnormality 18% Multiple abnormalities 2%

  7. PREVALENCE OF TYPE 2 DIABETES IN ASIA AND PACIFIC Age-standardised to Segi’s world population 35-64 years except: * ³40 **30-59 ‡ 30-69 #20-64 § 40-69

  8. 2000 2025 THE GLOBAL BURDEN OF DIABETES (2000-2025) 38.4 37.5 30.7 18.6 24.5 57.2 16.7 25% 102% 22.8 47% 21.8 150% 9.1 39.3 140% 18.2 0.4 0.7 64% 116% * In million subjects World Developed Count. Developing Count. 2000 2025 154 m 300 m 55 m 72 m 99 m 228 m

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