The POWER of Cranberry seed extract together with the super-antioxidant AstaXanthin

1. Benefits of Taking AstaCran® The POWER of Cranberry seed extract together with the super-antioxidant AstaXanthin

2. Advantages of AstaCran® • AstaCran® has extremely good stability • NO harmful solvent residues • Flaxseed and fish oils have a very short shelf life • These oils actually become rancid in short time and can (in some cases) become carcinogenic • No other supplement provides such abalanced ratio of essential fatty acids • AstaCran ® is derived from highly-renewable and safe sources

3. Advantages ofAstaCran® • Source of balanced EFA’s • Super Antioxidant • Aids in maintaining cardiovascular health • Aids with cholesterol management • Protects skin and eyes from photic injury • Reduce risk factors associated with macular degeneration • “Anti-Aging” properties via reduction of oxidative stress • Balanced EFA’s and super antioxidant in a single dose (Savings $$)

4. AstaCran® • Cranberol™ • Cranberry seed extract • Zanthin™ • Astaxanthin complex

5. Cranberol™ • Cranberry seed extract • Cranberry seeds • Supercritical CO2 extraction method • NO harmful solvent residues • High amounts of Essential Fatty Acids (EFA’s) • Omega-3 and Omega-6 • Also possesses antioxidants • High levels of Phytosterols Cranberries Vaccinium macrocarpon

6. Cranberry Seed Extract • Super Critical CO2 extraction • Extraction performed under high pressure using CO2 as a solvent • When extraction is complete, CO2 gas leaves NO residue (This may not be true with other commonly used solvents) • This is an exception, not the standard • Highly sustainable source of a balanced ratio of Essential Fatty Acids (EFAs)

7. Essential Fatty Acids • Polyunsaturated Fatty Acids(PUFAs) “double bond” • Omega-3 and Omega-6 • Essential because your body doesnot produce them. Acquired from diet or food supplements • Nutritionists have found that a balanced Omega-6/Omega-3 ratio of 1:1 is best for optimal health

8. EFA’s – Omega-6 & Omega-3 • The current western diet: • 15:1 and higher ratio • Recommended dietary ratio: • Between 5:1 and 10:1 • 1:1 ratio in humans is ideal • The best supplemental source should have as close to a 1:1 ratio as possible

9. Omega-6 This converts in the body to gamma-Linolenic acid (GLA) and then to prostaglandins that help regulate inflammation and blood pressure, as well as heart functioning. • Linoleic acid (LA) • Most commonly produced Essential Fatty Acid in agricultural seed oil production • Majority intake from vegetable oils • Highly unbalanced amounts of LA are bad because they promote inflammation, which can lead to many health problems • Primarily beneficial when in balance with Omega-3’s Alpha-Linoleic Acids (ALAs)

10. Omega-3 • άLinolenic acid (ALA) • High concentrations of Omega-3 improves vitality of the skin • Absorption is enhanced when combined with Omega-6 • As our diets have changed, Omega-3 consumption has decreased to a ratio that is associated with degenerative conditions • Omega-3 helps reduce LDL cholesterol

11. Other Sources • Other EFA sources • Fish and shellfish • Flaxseed (linseed) • Canola oil, hemp oil, soya oil • Chia seeds, pumpkin seeds, sunflower seeds • Leafy vegetables and walnuts • AstaCran can replace ALL other supplemental EFA sources (BIG savings)

12. Cranberol™ Antioxidants • Tocopherols • Vitamin E family • Powerful antioxidant • Tocotrienols • Also a form of Vitamin E • 40-60x stronger than tocopherols as an antioxidant

13. What is an Antioxidant? • An·ti·ox·i·dant • A substance (as beta-carotene or vitamin C) that inhibits oxidation or reactions promoted by oxygen, peroxides, or free radicals. Merriam-Webster Online • It gives, takes, or traps an electron.

14. Phytosterols • Phytosterols play an important role in maintaining a healthy cholesterol level • Reduces cholesterol absorption in the intestines • Similar chemical structures that compete with cholesterol for absorption. • Significant for cardiovascular health • Beta-sitosterol • Helps reduce blood levels of cholesterol • Stigmasterol

15. Cholesterol • Low Density Lipoproteins (LDL) • So called “Bad” cholesterol. • Transports cholesterol into the arteries. • High Density Lipoproteins (HDL) • So called “Good” cholesterol • Suspected to carry cholesterol from within* arteries to liver for redistribution or expulsion *ath·er·o·ma - 1:  Fatty degeneration of the inner coat of the arteries 2:  An abnormal fatty deposit in an artery Merriam-Webster Online

16. Cranberol™ • Cranberol can aid and supporta healthy cardiovascular system • Aid in maintaining healthy cholesterol levels • Aid in reduction of oxidative stress • Desirable source for a balanced ratio of EFA’s • Doesn’t turn rancid like many other sources of EFA’s

17. Zanthin® • Astaxanthin complex • Super-antioxidant • Prevents oxidative damage • 418g Atlantic Salmon = 3mg of astaxanthin.(1 pound = 453.59237 grams) Fish is becoming less desirable as a source for necessary compounds due to a concern over the rising levels of mercury, and various other heavy metals.

18. Source of Zanthin® • Haematococcus microalgae • Haematococcus pluvialis • Unicellular green algae • Found in Freshwater bodies Distribution of Astaxanthin stereo isomers in selected organisms (Bjerkeng1997)

19. Haematococcus Pluvialis • Potent source of astaxanthin • Highly renewable • Safe • Grown in a controlled environment

20. Other Sources • Abundant in Nature (in water) • Found in Salmon, Trout, Crustaceans, Crawfish,Pacific Cod, Scallops, Mackerel, Flounder, and other commercial seafood • Renewable

21. Astaxanthin Concentration

22. Zanthin® • Astaxanthin • Super-antioxidant • Properties of Astaxanthin • Decreased DNA damage. • Arrests mitochondrial free radicals

23. AstaZanthin™ Standardized Extract Natural Lycopene Synthetic Astaxanthin Natural alpha-tocopherol Natural a-b Carotene mix Natural Tocotrienols Natural Lutein Natural Beta Carotene 1.380 0.596 0.419 0.381 0.345 0.318 0.280 0.242 Antioxidant Studies ORAC – Oxygen Radical Absorbance Capacity Anti Oxidant Studies Naguib, Y., "Antioxidant Activities of Astaxanthin and Related Carotenoids,"Journal of Agricultural and Chemistry, v.48 (4), pp. 1150-1154.

24. Astaxanthin • Astaxanthin was 10 - 50 times stronger than vitamin E in the lipid peroxidation of mitochondria membranes using the TBA method Inoue (1990) • Astaxanthin is 10 times stronger than zeaxanthin, lutein, beta-carotene and canthaxanthin • Astaxanthin is 100 times greater than alpha-tocopherol against active oxygen species in the thiobarbituric assay Miki (1991)

25. Strength and Endurance • Fitness (submaximum load – Astrand method) • Strength/Explosivity (Wingate method of maximum effort) • Endurance (knee-bending technique) Malmsted, C.L. Gustavsberg, Sweden 6 Month Treatment Pre-treatment standardized exercise tests/endurance (p<0.05) Significant Improvement in strength/endurance (p<0.05) “Dietary Supplement with Astaxanthin-Rich Algal Meal Improves Muscle Endurance - A Double-blind Study on Male Students” N=40

26. Strength and Endurance • Increased Carotenoid content