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Sick Individuals and Sick Populations: High Risk and Population Based Approaches. Sir Geoffrey Rose. British Epidemiologist A Former Clinician Foundational Contribution to Public and Population Health The Principles of Population Strategies. The Strategy In Rose ’ s Time.
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Sick Individuals and Sick Populations: High Risk and Population Based Approaches
Sir Geoffrey Rose • British Epidemiologist • A Former Clinician • Foundational Contribution to Public and Population Health • The Principles of Population Strategies
The Strategy In Rose’s Time • A Clinical Strategy – Physician Strategy • People were sick and became Patients • Intervention usually when the disease was entrenched and often well advanced • Prevention was not as important a concept • Sometimes Patients are created e.g. HBP • Public Health Strategies were educational and addressed those at risk
Rose’s Questions • “Why do some individuals have hypertension”? • “Why do some populations have more hypertension” and other less? • What is responsible for the case? • What is responsible for the incidence in a population?
Distribution of Systolic BP in two Populations • In both populations if you only ask what is associated with the cases then the answer will be much the same – genetics, environment, behaviour • Looked at in isolation the greater question is obscured – “why is there much more elevated BP in London and much less in Kenya
What is Normal • If we understood the factors that lead to lower BP in Kenya then there is no reason why the application of those factors in London could not produce the same result • The conclusion is: - the population distribution can be shifted – in this case the curve could move to the left – the “normal”of this population need not be accepted as normal and indeed it may not be OK – and could potentially look like that of Kenya (or closer to that of Kenya) and thus make for a healthier society
What do we Conclude? • We need to be able to observe at population levels and not just individual levels • The find the determinants of incidence and prevalence rates, we need to study the characteristics of populations, not characteristics of individuals. • Accepted normal values may not be normal and they may not be OK
What do we Conclude? (2) • Curves of Risk can be shifted • Cardiovascular Disease is a largely preventable disease • We can confirm this by population trends e.g. Canada CAD mortality declines • Migration Patterns – Asians to North America – curve shifts to the right – adopt lifestyles of the new country
Learning from The Cholesterol Distribution Curve • Most of the excess deaths occur in the population in the middle of the curve at moderate values • There is high mortality at the high levels but there are far fewer people • In a population a large number of people at smaller risk will give rise to more cases of disease than a small number of people at high risk
The Conclusion • High risk levels of a factor may affect relatively few people in the population • A very large number of people exposed to a lesser or moderate risk leads to the majority of the cases in the population
The Case for a Population Strategy • If our health system focuses only on those who are at high risk or are sick; if we employ only clinical strategies we will miss the majority that contribute most to the overall mortality • A population preventive strategy that seeks to move the entire population distribution curve to the left is essential
The Population Approach • Both populations and high risk groups plus vulnerable population • Creates environments supportive of health • Focuses on health promotion and disease prevention • Works through partnerships and coalitions • Includes inter-sectoral and interdisciplinary groups and organizations • Uses healthy public policy development and community mobilization as major tools.
What Can We Conclude? • Since most cases arise in the middle of the curve • Since population curves can potentially shift • Since small changes which occur over an entire population produce great population benefits (though small individual benefits) • Therefore a population health approach is essential if risk is to be reduced and consequently morbidity and mortality
The Context • Social Motivation: • Change social values/norms • Marketing (social) • Marketing as a challenge • $$$$$ to influence behaviour • To influence mass behaviours then must influence mass determinants and they are economic and social
Conclusion Rose has lead us to an understanding of: • Observing populations to understand the reasons for incidence and prevalence is essential • Risk distribution at a population level can be improved (move the curve) • Most cases do not arise from the high risk group • To improve health need a population health strategy to complement a high risk strategy