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Algorithms Organization

Algorithms Organization. Ross Whitaker – Utah Polina Golland – MIT ( Kayhan B.) Guido Gerig – Utah Martin Styner – UNC Allen Tannenbaum – Georgia Tech. Presentations. Highlights from the 10-year project Clinical/biomedical impact Recent advances Future. Diffusion Tensor Imaging.

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Algorithms Organization

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  1. Algorithms Organization Ross Whitaker – Utah PolinaGolland – MIT (Kayhan B.) Guido Gerig – Utah Martin Styner – UNC Allen Tannenbaum – Georgia Tech

  2. Presentations Highlights from the 10-year project Clinical/biomedical impact Recent advances Future

  3. Diffusion Tensor Imaging • Structure, function, connectivity, and schizophrenia • Shenton/Harvard • Potkin/Irvine • Technical challenges • Data preprocessing • Robust tools for analysis

  4. DTI Technical Development • Denoising • Basu, et al., MICCAI, 2006 • Susceptibility artifacts • Tao, et al., IPMI 2009 • Segmentation • Fletcher et al., IPMI, 2007

  5. DTI Segmentation • Volumetric tractography • Volumetric paths between ROIs • A collection of shortest paths • User interaction, visualization, GPU implementations

  6. NA-MIC DTI Analysis • Ancillary grant: Lainhart/Fletcher – DTI analysis in autism • Scientific results • Arcuatefasciculus in autism, Fletcher et al, Neuroimage, 2010. • Longitudinal Heschl'sgyrusin autism, Prigge et al., 2013. • Software pipeline • Impact • Cardenas et al., J Neuroimaging, 2013. (UCSF)

  7. Statistical Shape Modeling • DBPs • Shenton/Schizophrenia • Piven/Autism • MacLeod/Marrouche • Robust, general methods for shape analysis • Software • ShapeWorks

  8. Technology for Shape Analysis • Correspondence/parameterization • Hypothesis testing • Regression • Longitudinal analysis • Scientific results • Harris et al., J. of Ortho. Res., 2013 • Jones et al., J. of Ortho. Res., 2013

  9. NA-MIC Ancillary Grant • Anderson: shape analysis in hip pathoanatomy (Aug 2013) • Shape analysis in hip biomechanics • Diagnosis and treatment planning • Database of parameterized hip models

  10. Segmentation • DBPs • Sharp/Chen, Head and Neck Cancer • MacLeod/Marrouche, Afib • Robust tools for “difficult” segmentation problems • Low SNR • High shape variability

  11. Bayesian Formulation of LA Segmentation (DCE-MRI)

  12. LA Segmentation Results

  13. NIH Proposal – Afib(Oct 2013) CARMA (Cates, Marrouche, et al.) Shape analysis afib/stroke

  14. Slicer Module

  15. Slicer Module (In Progress) • Cleaver – triangle/tet meshing of multmaterial volumes • Visualization, simulation

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