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Thoracic surgery. Thoracic Surgery Department Regional Hospital for Lung Diseases Szczecin Zdunowo, Poland. Long time ago. Much later. Main carcinogenic factors. Chemicals Asbestos Benzidine methyl eter Vinyl chloride Aromatic hydrocarbons CIGARETTE SMOKING. Occupational exposure
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Thoracic surgery Thoracic Surgery Department Regional Hospital for Lung Diseases Szczecin Zdunowo, Poland
Main carcinogenic factors • Chemicals • Asbestos • Benzidine • methyl eter • Vinyl chloride • Aromatic hydrocarbons CIGARETTE SMOKING • Occupational exposure • Coal gasification • Hematite and uranium mining • Contact with arsene, nickel, beryl, chrome
So called early lung cancer symptoms • Cough • Hemoptysis • Intrathoracic pain • Recurrent pneumonias • Are those symptoms really early?
Paraneoplasmatic symptoms • Cushing syndrome • Hipercalcemia • Gynaecomastia • Polymyosistis • Peripheral neuropathy • Myasthenia • Proliferatic osteoarthropathy • Lupus erythematosus • Acanthosis nigricans • Anaemia, leucopenia • Thrombocytopaenia • Thrombophlebitis migrans • Aseptic endocarditis
Diagnosis • Radiology: X-ray, CT, NMR, USG, scintigraphy • Pathology: sputum cytology, endoscopy, FNAB mediastinoscopy, VATS, explorative thoracotomy • Genetics: p53, k-ras, CEA, cyfra 21-1, myc
Contraindications for surgery • Dissemination • Horner`s syndrome • Vena cava syndrome • Vocal cord paresis • Pancoast syndrome • WHO>2
Surgical approach • Antero- and anterolateral • Posterolateral • Sternotomy • Clamshell • Paulson • Mixed
Types of surgery • Pneumonectomy • Lobectomy (incl. sleeve) • Segmentectomy • Wedge or marginal resection • VATS
Pneumothorax • Close • Open • Tension
Treatment • Bed rest • Drainage • Pleurectomy