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The development of biologically active medication to treat TBC patients

The development of biologically active medication to treat TBC patients. Malkov S . А., Shironosov O . V ., Shironosova G . I. PROBLEM TOPICALITY. Every year TBC causes the following : 1 billon people infection ; 8-10 billion people illness ;

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The development of biologically active medication to treat TBC patients

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  1. The development of biologically active medication to treat TBC patients MalkovS. А., ShironosovO.V., ShironosovaG.I.

  2. PROBLEM TOPICALITY Every year TBC causes the following: 1 billonpeople infection; 8-10 billionpeople illness; 3-4 billionpeopledeath. WHO declared TBC the global danger in 1993.

  3. Modern TBC patient treatment • Is expensive (the average cost of one bed day -1600 rubles); • Causespoisonouseffect; • Requireslong-term (4-6 months) administration; • Is aggravated by multidrug resistance.

  4. Galleria Mellonella – The Greater Wax Moth • I.I. Mechnikov (1889); • S.А. Mukhin (1955); • N.А. Spiridonov (1989). Extract's properties: • Immune protective; • Antimicrobial; • Antioxidant.

  5. HOW TO GET A BIOACTIVE PRODUCT FROM THE GREATER WAX MOTH LARVAE(21)4938002/14 (22) 2603.91 (46)2706.95 Bulletin №18 (71) Institute of Theoretical and Experimental Biophysics, USSR Academy of Sciences(72) SpiridonovNA; RachkovAK; Mukhin SA; Kondrashova MN. (73) Spiridonov Nikolay Aleksandrovich(55) USSR certificate of authorship N 1284229, А 61К 35/04. 1989.

  6. The way of noncontact activation Solutionswithnegative redox potential

  7. THE PROJET’S AIM is the development of bioactive medication (with long-lasting redox potential) on the basis of water solutions of The Greater Wax Moth larvae to treat TBC patients.

  8. DYNAMICS OF REDOX POTENTIAL CHANGE

  9. Clinical research Republican tuberculosis dispensary: • 15 patients; • Infiltrative TB. • Average age - 40 years; • Gender - male; • Treatment duration – 3,5 months.

  10. Research results • twofold reduction of abacillary duration; • reduction of intoxication; • improvement of blood value (reduction of the number of lymphocytes, improvement of differential blood cell count, ESR reduction, etc.).

  11. Commercialization perspectives • Bed day shortening by 1,5-2 times. • Treatment course depreciation. • Increase of medication’s biological activity .

  12. Demand assessment after launching

  13. GRNT - GLOBAL RESONANCE NONLINEAR TECHNOLOGIES Thank You and Be Healthy! http://grnt.biz

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