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Myasthenia Gravis

Myasthenia Gravis. Blaine Suing November 21 st 2007. HERE WE GO !. What is Myasthenia Gravis?. Myasthenia gravis is a chronic autoimmune neuromuscular disease The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness."

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Myasthenia Gravis

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  1. Myasthenia Gravis Blaine Suing November 21st 2007

  2. HERE WE GO!

  3. What is Myasthenia Gravis? • Myasthenia gravis is a chronic autoimmune neuromuscular disease • The name myasthenia gravis, which is Latin and Greek in origin, literally means "grave muscle weakness." • Myasthenia gravis is muscle weakness that increases with activity and improves after periods of rest.

  4. Where does the disease take place? • Myasthenia Gravis takes place a the neuromuscular junction.

  5. The areas that are most affected. • Myasthenia Gravis mainly effects the eye lids, eyes, and facial movement (such as chewing or talking) which are all voluntary muscles. • It may also affect the muscles that control breathing, neck and limb muscles.

  6. WARNING! NEXT SLIDE CONTAINS GRAPHIC CONTENT. VIEWERS DISCRESSION IS ADVISED!

  7. www.nanosweb.org/.../images/mythenia_1.jpg

  8. Who does this affect? • Both men and women can have the disease. Men over the age of 60 and women under the age of 40 are more likely to have it. But in can come at any age. • Juvenile myasthenia gravis is not un common. • Neonatal myasthenia gravis is temporary and usually only last 2-3 months.

  9. Women are affected more then men at ratio 3/2. • In the united states for every 100,000 people, there are 14 people with myasthenia gravis.

  10. Treatment • The first attempt to treat MG was on June 2nd of 1935. • This was an injection of physostigmine. • It was performed by Dr. Mary B. Walker.

  11. Treatment (today’s) • There are different forms of treatment in today's world. • Oral pills • prednisone, azathioprine, cyclosporine • IV • Gammagard, Gammar-P, Sandoglobulin • Surgery • Thymectomy

  12. Patient Out look • Most patients with Mg can control it with medications or surgery. • Only in severe cases is were the patient may have repertory distress secondary to fever or infection.

  13. New Studies • One such study is testing the use intravenous immune globlin. • Experts are studying the use of EN101 antisense

  14. Diagnosing • Weakness in a specific area. • Decrease strength through out the day. • Rejuvenated with rest.

  15. Conflicting evidence • Is thymectomy really curing the disorder, or is stopping the progression?

  16. Credits • http://www.neurology.org 14 Aug 2007 • http://www.mayoclinic.com/health/myasthenia-gravis Jan 19 2007 • National Institute of Neurological Disorders and StrokeNovember 19, 2007 • National Institutes of HealthNovember 19, 2007 • www.mgauk.org September 2005

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