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4-Dimensional Treatment Planning of Lung Tumors

4-Dimensional Treatment Planning of Lung Tumors. Lung Cancer. 1 out of 14 people will be diagnosed with lung cancer at some point in their life! 90% of lung cancer is caused by SMOKING. 5 years after diagnosis, only 16% survive!. Treatment Options. Surgery Chemotherapy Radiation Therapy

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4-Dimensional Treatment Planning of Lung Tumors

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  1. 4-Dimensional Treatment Planning of Lung Tumors

  2. Lung Cancer • 1 out of 14 people will be diagnosed with lung cancer at some point in their life! • 90% of lung cancer is caused by SMOKING.

  3. 5 years after diagnosis, only 16% survive!

  4. Treatment Options • Surgery • Chemotherapy • Radiation Therapy • Photons • Protons

  5. Photons v. Protons

  6. 1 Original Deformed dose Accumulated dose More distal lung is irradiated WIP Brown Bag March 3, 2009 Room view Organ view Voxel view

  7. LungEUD1 Analysis GTY Chen Ashley Rubenstein et al September 28, 2010

  8. EUD1 Fovia

  9. Ant Field GIF no distal margin

  10. Post Field GIF

  11. Observations • With post field, there is range perturbation distal to target during motion • More normal lung is irradiated • Distal lung density is altered; so deeper geometric penetration. • Therefore EUD could change in 4D planning vs 3D planning. Magnitude depend on degree of motion and compensator design.

  12. EUD2 Analysis GTYC / AER September 28, 2010

  13. LPO single field dose Gif

  14. Post Obliques 2F plan GIF

  15. EUD3 Analysis Sept 28 2010

  16. Single field dose distribution

  17. Single field dose distribution

  18. Single field dose distribution

  19. Plan • 4 field plan • Quite robust to motion! • Use more fields in proton lung!

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