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Competitors. Competitors : ELISA. Focus Diagnostics Dengue Fever Virus IgM Capture DxSelect TM Focus Diagnostics Dengue Fever Virus IgG DxSelect TM. Focus Diagnostics Dengue Fever Virus IgM Capture DxSelect TM. 3 hr 45 minutes incubation time (over 1 hour longer than P anbio )
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Competitors: ELISA • Focus DiagnosticsDengue Fever Virus IgM Capture DxSelectTM • Focus Diagnostics Dengue Fever Virus IgG DxSelectTM
Focus DiagnosticsDengue Fever Virus IgM Capture DxSelectTM • 3 hr 45 minutes incubation time (over 1 hour longer than Panbio) • 7 steps required (Panbio has 6 steps) • Has been compared to Panbio Dengue Duo IgG & IgM Capture ELISA (Cuzzubbo et al., 1999, Clin. Diagn. Lab. Immunol., 6(6):705-712.) • Overall performance of the Panbio Dengue Duo was higher than the MRL/Focus Diagnostics ELISA. • MRL/Focus Diagnostics IgM ELISA has a lower cut-off than the Duo and consequently a higher sensitivity (94% vs 89%)
Focus DiagnosticsDengue Fever Virus IgM Capture DxSelectTM • Focus ELISA is less specific in infections other than dengue than the Panbio kits. • Panbio Dengue Duo 79% specificity in JE and 100% specificity in non-flavivirus infections • Focus/MRL 25% specificity in JE & 91% in non-flavivirus infections.
Focus DiagnosticsDengue Fever Virus IgG DxSelectTM • 1 hr 45 minutes incubation time (Panbio only 1 hr 10 min) • 6 steps required (Panbio only has 5 steps)