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Plate 53

Plate 53. Nonspecific Resistance to Disease: Inflammation. Nonspecific Resistance. Inflammation is the same against all microorganisms (hence nonspecific ) Inflammation can occur even if a sterile object is used Inflamed = to be flamed (heated, turns red). Inflammation.

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Plate 53

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  1. Plate 53 Nonspecific Resistance to Disease: Inflammation

  2. Nonspecific Resistance • Inflammation is the same against all microorganisms (hence nonspecific) • Inflammation can occur even if a sterile object is used • Inflamed = to be flamed (heated, turns red)

  3. Inflammation • Occurs in lower layers of skin (dermis) • Contains: • Blood vessels • White blood cells • Connective tissue • Nerve cells

  4. Purpose of Inflammation • Prevents the growth of microorganisms • Heat inhibits the reproduction of bacteria • Phagocytes consume bacteria cells • Repairs mechanical damage • Rebuilds damaged tissues

  5. Symptoms of Inflammation • 4 defining symptoms: • Heat • Swelling • Pain • Redness

  6. Beginning of Inflammation • Damaged tissues release histamines, which increase blood flow to the injured area • Results in redness • Capillaries leak phagocytes and clotting proteins into the wound • Results in swelling and heat

  7. Phagocytosis • Neutrophils (white blood cells) phagocytize the following materials: • Bacteria • Dead cells • Debris • After filling with material, neutrophils die (and become pus)

  8. http://www.youtube.com/watch?v=suCKm97yvyk&feature=related

  9. Healing • After all foreign material is removed, blood vessels decrease in size and quantity • Fibroblasts create new fibers (fibrosis) in the injured area, sometimes resulting in scar tissue

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