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Designer Genes: pLym

Designer Genes: pLym. A Presentation by Megan HInes. Brittany Daniel, Actress. What is non-Hodgkin’s Lymphoma?. A cancer of lymph tissue No initial cause Affects those of any age but almost half that are affected are over age 65

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Designer Genes: pLym

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  1. Designer Genes: pLym A Presentation by Megan HInes

  2. Brittany Daniel, Actress

  3. What is non-Hodgkin’s Lymphoma? • A cancer of lymph tissue • No initial cause • Affects those of any age but almost half that are affected are over age 65 • Symptoms- swollen lymph nodes on neck, armpits, groin; abdominal pain or swelling; chest pain, coughing or trouble breathing; fatigue, fever, night sweats, weight loss • Treatment depends on the symptoms, stage/location of the disease, and the age/health of the patient.

  4. How does plym save lives? • Vector: The pLym is inserted into the retrovirus (aka deadened cell). • Den-ase: The operon will be turned on in the presence of intestinal microbiota to trigger transcription. • GLP: Growing Lymph Protein, begins transcription in the presence of Den-ase. • *Intestinal Microbiota – the bacteria that lives in the human gut; cancer of white blood cells GLP ORI pLym Den-ase

  5. Early Detection (the pill) This pill will be taken with the bacteria in it where the GLP will glow.

  6. Lymphoma Awareness

  7. FDA Compliance Guidelines • http://www.fda.gov/iceci/compliancemanuals/compliancepolicyguidancemanual/ucm074396.htm

  8. Work Cited • "Result Filters." National Center for Biotechnology Information. U.S. National Library of Medicine, 15 July 2013. Web. 24 Mar. 2014. • "Swollen Lymph Nodes: Causes, Symptoms, and Treatment." WebMD. WebMD, 6 Dec. 2012. Web. 24 Mar. 2014.

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