Nursing Care and Interventions in Managing Chronic Renal Failure

1. Keith Rischer RN, MA, CEN Nursing Care and Interventions in Managing Chronic Renal Failure

2. Todays Objectives… Review the pathophysiology and causes of chronic renal failure (CRF). Contrast lab findings and physiologic changes associated with acute vs. chronic renal failure. Identify relevant nursing diagnosis statements and prioritize nursing care for clients with CRF including dietary modifications. Compare and contrast the following treatment modalities: peritoneal dialysis, hemodialysis, and continuous renal replacement therapies. Identify nursing care priorities with hemodialysis and peritoneal dialysis. Prioritize teaching needs of clients with CRF.

4. Patho

5. Patho:Chronic Renal Failure • Progressive, irreversible kidney injury • Kidney function does not recover • Azotemia • Increase nitrogenous wastes such as BUN • Creatinine • Uremia • azotemia with symptoms (chart 75-5 p.1739) • Anorexia, N&V, fatigue, SOB • Uremic syndrome (urine in the blood) • Altered fluid, lyte and acid-base balance • clinical and lab manifestations of renal failure • More severe weakness, lethargy, confusion…coma..death

6. Patho:Stages of Chronic Renal Failure • Diminished renal reserve • GFR ½ normal • Compensation w/healthy nephrons • Renal insufficiency • Nephrons destroyed…remaining adapt • BUN, creatinine, uric acid elevate • Priorities: fluid volume, diet, control of HTN, • End-stage renal disease • Severe fluid, acid-base imbalances • Dialysis needed or will die

7. Patho:Physiologic Changes • Kidney • Decreased GFR • Poor H2O excretion • Metabolic • BUN and creatinine increased • Electrolytes • Sodium- later stages sodium retention • Potassium increased • EKG changes • Kayexelate • Acid-base balance: metabolic acidosis • Calcium decreased and phosphorus increased

8. Patho:Physiologic Changes • Cardiac • Hypertension • Hyperlipidemia • Congestive heart failure • Uremic pericarditis • Hematologic • anemia • Gastrointestinal • Halitosis • Stomatitis • PUD

9. Patho:Physiologic Changes • Neurologic • lethargy • Uremic encephalopathy • Respiratory • pulmonary effusion • SOB • Urinary • proteinuria, oliguria, dilute • Skin • dry, pallor, pruritus, ecchymosis

10. Drug Therapy chart 75-3 p.1737 • Cardioglycides • Digoxin/Lanoxin • Calcium channel blockers • Diuretics • Vitamins and minerals • Folic Acid • Ferrous Sulfate • Biologic response modifiers • Erthropoetin (Epogen) • Phosphate binders • Aluminum hydroxide • Stool softeners and laxatives

11. DM II Retinopathy ESRD…hemodialysis 3x/week Anemia CAD PTCA 1994 w/redo 2005 AMI 2005-stent to LAD, Cx CHF 25% EF w/global hypokinesis and severe inferior hypokinesis AFib AAA Neuropathy Obesity Rt Femoral Bypass Rt BKA Medications ASA Phoslo Coumadin Digoxin Epoetin Lantus insulin Novolog per sliding scale Lipitor Neurontin NTG subl prn Patho of One Dialysis/ESRD Client

12. ED Renal Case Study • 69yr female • HPI: Hemodialysis earlier in day. Found to have HR in the 40’s afterwards. Did not increase. Has no c/o lightheadedness. Has no other physical c/o • VS: T-97.8 P-42 (AFib) R-20 BP-122/76 sats 96% 3l per n/c

13. Labs

14. Excess Fluid Volume • Interventions: • Monitor I&O • Promote fluid balance • Daily weights • 1 kg=1liter fluid • Assess for manifestations of volume excess: • Crackles in the bases of the lungs • Edema • Distended neck veins • Diuretics • Contraindicated w/ESRD

15. Decreased Cardiac Output • Interventions: • Control hypertension • calcium channel blockers • ACE inhibitors • alpha- and beta-adrenergic blockers • vasodilators. • Education: • monitor blood pressure • client’s weight • Diet • Drug regimen

16. Potential for Pulmonary Edema • Interventions: • Assess for early signs of pulmonary edema • Restlessness/anxiety • Tachycardia • Tachypnea • oxygen saturation levels • Crackles in bases • Hypertension

17. Imbalanced Nutrition • Interventions: • Dietary evaluation for: • Protein • Fluid • Potassium • Sodium • Phosphorus • Vitamin supplementation • Iron • Water soluable vitamins • Calcium • Vitamin D

18. Risk for Infection • Interventions: • Meticulous skin care • Preventive skin care • Inspection of vascular access site for dialysis • Monitoring of vital signs for manifestations of infection

19. Risk for Injury • Interventions: • Drug therapy • Education • prevent fall • Injury • pathologic fractures • bleeding • toxic effects of prescribed drugs • Digoxin • Narcotics • Heparin or Coumadin

20. Fatigue • Interventions: • Assess for vitamin deficiency • Administer vitamin and mineral supplements • anemia • Give iron supplements as needed • Erythropoietin therapy • Buildup of urea

21. Anxiety • Interventions: • Health care team involvement • Client and family education • Continuity of care • Encouragement of client to ask questions and discuss fears about the diagnosis of renal failure

22. Indications for Dialysis Uremia Persistent hyperkalemia Uncompensated metabolic acidosis Fluid volume excess unresponsive to diuretics Uremic pericarditis Uremic encephalopathy

23. Hemodialysis • Client selection • Irreversible renal failure • Expectation for rehab • Acceptance of regimen • Dialysis settings • Acute-hospital • Out patient centers

24. Hemodialysis:Patho • Diffusion • Dialysate • Lytes and H2O • Dialyzer • Anticoagulation • Heparin to prevent blood clots in dialyzer or tubing

25. Complications of Hemodialysis Dialysis disequilibrium syndrome Infectious diseases Hepatitis B and C infections HIV exposure—poses some risk for clients undergoing dialysis

26. Vascular Access • Arteriovenous fistula, or arteriovenous graft for long-term permanent access • Hemodialysis catheter, dual or triple lumen, or arteriovenous shunt for temporary access • Precautions • Bruit & thrill • BP restrictions • Complications • Thrombosis • CMS

27. Hemodialysis: Nursing Interventions • Predialysis care: • Medications to hold…why? • Postdialysis care: • Monitor for complications such as hypotension, headache, nausea, malaise, vomiting, dizziness, muscle cramps. • Monitor vital signs and weight. • sepsis • Avoid invasive procedures 4 to 6 hours after dialysis. • Continually monitor for hemorrhage. • Assess for thrill • No BP or blood draws on arm

28. Peritoneal Dialysis

29. Peritoneal Dialysis • Phases • Inflow • Dwell • Drain • Contraindications • history of abd surgeries • recurrent hernias • excessive obesity • preexisting vertebral disease • severe obstructive pulmonary disease

30. Complications of Peritoneal Dialysis • Peritonitis (cloudy outflow) • Pain • Exit site and tunnel infections • Poor dialysate flow • Dialysate leakage • Monitor color of outflow • cloudy (peritonitis) • brown (bowel) • bloody (first week OK) • urine (bladder)

31. Nursing Care During Peritoneal Dialysis • Pre PD: • Vital signs pre and q 15-30” during • Weight • laboratory tests • Continually monitor the client for: • respiratory distress • pain • discomfort • Monitor prescribed dwell time and initiate outflow • Observe outflow amount & pattern of fluid

32. Education Priorities Pathophysiology and manifestations Complications When to call the doctor Keep record of all labs Take medications and follow plan of care set out by case manager Monitor weight, fatigue levels closely