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Polygenic Inheritance

Polygenic Inheritance . Hair Color . What is going on here?. Polygenic vs. Multiple Alleles . Multiple Alleles: Blood Type Phenotype- A, B, AB, O blood type Alleles I A I B I O ONE gene, with 3 alleles . Polygenic : Hair color Many genes affecting one trait MANY PHENOTYPES! .

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Polygenic Inheritance

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  1. Polygenic Inheritance

  2. Hair Color • What is going on here?

  3. Polygenic vs. Multiple Alleles • Multiple Alleles: Blood Type • Phenotype- A, B, AB, O blood type • Alleles IA IB IO • ONE gene, with 3 alleles • Polygenic: Hair color • Many genes affecting one trait • MANY PHENOTYPES!

  4. Polygenic Inheritance • Different genes contributing to the phenotype. #4 #12 #13

  5. How do many genes give so many phenotypes? Flower Color What is going on here? • AABBDD Burgundy • Polygenic Inheritance • Many contributing genes to one trait • How many genes? • 3 • How many phenotypes? • 6 • AABBDd Dark red • AABBdd Red • AABbdd Dark pink • AAbbdd Pink • Aabbdd Light pink • aabbdd White • Each “capital” is anadditive allele adding to the pigment

  6. How many genes are involved?

  7. Polygenic Traits • Quantitative Traits: • Phenotypes vary in degree • Skin color and hair color • Other examples? • Height • Eye color • Weight

  8. Polygenic Simulation Questions to keep in mind • How do parents pass on genes for height to their children? • Is anyone taller than both of their parents? How can the genes contribute to this?

  9. Class Data

  10. Histogram

  11. How can a child be taller than his parents?

  12. Environment Influenced by the genes and environment • Height? • Skin color ? • Weight?

  13. Exit Ticket • Americans used to be the “tallest” nation from about 1800-1950. Recently many industrialized European countries are now “Taller” ( Holland is #1). Why do you think? • How tall will your child be? • Take your height based off the polygenic traits of the simulation and assume the height of your partner. What possible heights could your child be?

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