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Phenotype Annotation at TAIR

Phenotype Annotation at TAIR. Tanya Berardini. Current Status. Phenotypes are associated to organisms (germplasms) and linked to references Curation is mainly done in unstructured full text Pilot study of structured annotation completed PaTO not yet implemented. papillae:abnormal

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Phenotype Annotation at TAIR

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  1. Phenotype Annotation at TAIR Tanya Berardini

  2. Current Status • Phenotypes are associated to organisms (germplasms) and linked to references • Curation is mainly done in unstructured full text • Pilot study of structured annotation completed • PaTO not yet implemented

  3. papillae:abnormal style:abnormal septum development:incomplete leaf:serrate

  4. Same challenges as other databases • Large corpus of literature • Set number of curators with many diverse responsibilities • Different ways of paper prioritization

  5. Capturing phenotypes from the literature • Single paper, describing single aspect of phenotype • Single paper, describing multiple aspects of the organism’s phenotype • Multiple papers describing different aspects of the organism’s phenotype • Multiple papers, describing the same phenotype

  6. Storing complex annotations in the database • Right now, GO as a model for assocations: • 1 association = 1 gene product + 1 CV term • How do we deal with multiple ontologies in one association? • 1 association = 1 germplasm + 1 anatomy term + 1 PATO term (+ others)

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