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Osteoscoop - Issue N°179 - April 2011

Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation. Osteoscoop - Issue N°179 - April 2011. Polycystin 1. ADPKD. Polycystic kidneys Hepatic cysts Pancreatic cysts Cerebral aneurysm Aortic aneurysm. Polycystin 1. ADPKD.

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Osteoscoop - Issue N°179 - April 2011

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  1. Conditional disruption of Pkd1 in osteoblasts results in osteopenia dueto direct impairment of bone formation Osteoscoop - Issue N°179 - April 2011

  2. Polycystin 1 ADPKD • Polycystic kidneys • Hepatic cysts • Pancreatic cysts • Cerebral aneurysm • Aortic aneurysm

  3. Polycystin 1 ADPKD • Polycystic kidneys • Hepatic cysts • Pancreatic cysts • Cerebral aneurysm • Aortic aneurysm Osteoblasts

  4. Polycystin 1 ADPKD • Polycystic kidneys • Hepatic cysts • Pancreatic cysts • Cerebral aneurysm • Aortic aneurysm AKT Runx2 Osteoblasts Osteoblast differentiation

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