1 / 18

Untreated chlamydial infection among adolescents and young adults in Baltimore, MD

Untreated chlamydial infection among adolescents and young adults in Baltimore, MD. Elizabeth Eggleston, DrPH 1 ; Susan M. Rogers, PhD 1 ; Charles F. Turner, PhD 2 , Anthony Roman, MA 3 ; Sylvia Tan, MS 1 ; Emily Erbelding, MD, MPH 4

caelan
Download Presentation

Untreated chlamydial infection among adolescents and young adults in Baltimore, MD

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Untreated chlamydial infection among adolescents and young adults in Baltimore, MD Elizabeth Eggleston, DrPH1; Susan M. Rogers, PhD1; Charles F. Turner, PhD2, Anthony Roman, MA3; Sylvia Tan, MS1; Emily Erbelding, MD, MPH4 (1) Statistics and Epidemiology, Research Triangle Institute, Washington, DC; (2) Queens College, City University of New York; (3) Center for Survey Research, University of Massachusetts-Boston; (4) Johns Hopkins University School of Medicine, Baltimore, MD. Presented atThe 136th Annual Meeting of the American Public Health Association San Diego, CA • October 25–29, 2008 Phone: 202.728.2080 Email: eeggleston@rti.org

  2. Chlamydia Trachomatis (CT) • Most frequently reported bacterial sexually transmitted infection in the U.S. • 348 cases per 100,000 population reported to CDC in 2006 – up 5.6% from 2005 • Reported rate among women 3 times higher than among men

  3. Chlamydia: morbidity Among women, untreated chlamydia may result in pelvic inflammatory disease (a major cause of infertility, ectopic pregnancy, chronic pelvic pain) Among men, CT associated with urethritis & epididymitis. Untreated CT infections facilitate HIV transmission among both men & women

  4. Chlamydia surveillance Laboratories and medical providers required by law to report diagnosed cases of chlamydia. Reported cases represent only those infections that are detected and, presumably, treated. Chlamydia infections are usually asymptomatic; 75% women and 50% men have no symptoms. Surveillance data reflect standard screening practices – CDC recommends testing all sexually active women under age 26 annually.

  5. Monitoring STIs Survey Program (MSSP) Continuous monitoring of three STIs (CT, Tv, GC) over three years in Baltimore, starting in 2006 Designed to address shortcomings of current surveillance methods (incomplete coverage, skewed in response to screening norms) Funding provided by NICHD Collaboration between RTI, Univ. of Mass-Boston, UNC-Chapel Hill, Johns Hopkins Univ. School of Medicine/BCHD

  6. MSSP, continued Data collection via TACASI interview and mailed-in urine specimens Study participants: aged 15-35, male and female, English speaking

  7. MSSP, Year 1 analysis In Year 1 (Sept 06 – Aug 07), 1248 Baltimore residents aged 15-35 completed a TACASI interview; 69% (n=866) provided a urine specimen. We calculate prevalence estimates of CT in the population. We assess associations between demographic/behavioral characteristics and CT prevalence using chi-square tests. We compare our study data to BCHD surveillance data. All MSSP data are weighted.

  8. MSSP: Estimated prevalence of chlamydia, overall and by gender and race

  9. MSSP: Estimated prevalence of chlamydia by age group

  10. MSSP: Estimated prevalence of chlamydia by marital status and education

  11. MSSP: Estimated prevalence of chlamydia by risk factors

  12. MSSP: Estimated prevalence of chlamydia by STI history

  13. Surveillance data Cases of CT infection reported to Baltimore City Health Dept. (BCHD) by medical providers and laboratories Percentages for population prevalences calculated using 2000 U.S. Census reports of population size as denominator Surveillance data grouped by age using U.S. Census age categories MSSP data presented for comparison with same age categories

  14. Surveillance data v. MSSP: Estimated chlamydia prevalence, ages 15-34

  15. Surveillance data v. MSSP:Estimated CT prevalence, by gender and race

  16. Surveillance data v. MSSP:Estimated CT prevalence, by age

  17. Conclusion Nearly 5% of 15-35 year-olds had an undetected chlamydial infection in MSSP. CT prevalence slightly higher among males and among blacks, but small sample sizes limit generalizability of these findings. Infections most prevalent among 18-23 year olds, those with least education Having multiple partners strongly associated with CT infection, even as few as 2 in past year. Previous infection strong predictor of current infection.

  18. Conclusion, continued Comparison of MSSP to surveillance data suggests that undiagnosed, untreated CT infections among 15-34 year-olds exceed diagnosed/reported infections by a factor of 1.3. Ct prevalence in MSSP higher among males than females, while opposite pattern emerges in surveillance data -- suggesting need for increased Ct screening among males.

More Related