1 / 7

Genetics IN BRIEF

Genetics IN BRIEF. Assume: large population, random mating Let: proportion of allele A = p proportion of allele a = q p + q = 1. Aa x Aa. p 2 + 2pq + q 2. Hardy-Weinberg equilibrium p 2 + 2pq + q 2.

caesar-bartlett
Download Presentation

Genetics IN BRIEF

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Genetics IN BRIEF Assume: large population, random mating Let: proportion of allele A = p proportion of allele a = q p + q = 1 Aa x Aa p2 + 2pq + q2

  2. Hardy-Weinberg equilibrium p2 + 2pq + q2 Χ2 = (1787-1782.7)2/1782.7 + (3037-3045.6)2/3045.6 + (1305-1300.7)2/1300.7 = 0.04887 Probability associated with this value and 1 d.f. = 0.90

  3. Factors that cause populations to go out of HWE Drift Mutation Immigration Selection Inbreeding/asexual reproduction Founder effects Bottlenecks

  4. Inbreeding Inbreeding coefficient (I)

  5. Fst = fixation index or amount of genetic differentiation among subpopulations Hs = 2pi(1-pi) Ht=2pi(1-pi) Fst=(Ht-Hs)/Ht Fst=∑pi(1-pi)Fst/ ∑pi(1-pi) .05-.15 = moderate differentiation .15-.25 = great differentiation

  6. Other genetic terms and calculations: Average Heterozygosity Genetic Diversity Genetic Distance Relatedness

  7. Example: Trillium maculatum

More Related