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NIRF

NIRF. Absorption coefficient (cm -1 ). Wavelength [nm]. Weissleder et al ., Nature Cancer Rev 2002 2(1):11-8. Proteasen sensitive KM. Enzym. Kein Signal. Signal. Weissleder et al ., Nature Biotech; 1999;17:375-378. MMP-Probe. Bremer et al . Nat Med (2001) 7 (6) 743-8. MMP-2 Probe.

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NIRF

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  1. NIRF Absorption coefficient (cm-1) Wavelength [nm] Weissleder et al., Nature Cancer Rev 2002 2(1):11-8

  2. Proteasen sensitive KM Enzym Kein Signal Signal Weissleder et al., Nature Biotech; 1999;17:375-378

  3. MMP-Probe Bremer et al. Nat Med (2001) 7 (6) 743-8

  4. MMP-2 Probe Fluoreszens [AU] Kontroll-Probe 0 300 600 900 1200 1500 Zeit [min] Enyzmatische Aktivierung

  5. Zellexperimente Genexpression:rt-PCR BT20 HT1080 MW-Standard -+ Bremer et al. Radiology 221 (2), 523-9 (2001)

  6. MMP-2 - MMP-2 + In-vivo Experimente Lichtbild MMP-2 - MMP-2 + NIRF-Bild Bremer et al. Radiology 221 (2), 523-9 (2001)

  7. 10-12 10-10 10-8 10-6 10-4 Inhibition der ProbenaktivierungAG3340 Fluoreszensanstieg [%] AG3340 [M] Bremer et al. Nat Med (2001) 7 (6) 743-8

  8. MMP-Hemmung Kontrolle AG3340 Bremer et al. Nat Med (2001) 7 (6) 743-8

  9. Fluorescence mediated Tomography Ntziachristos et al; Nat Med 2002

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