20 likes | 191 Views
Figure 1. A. B. Ag presenting cell. Ag presenting cell. MHC/Ag. B7-1/B7-2. MHC/Ag. Immune Synapse. BCR. TCR. CD28. CD19. T Lymphocyte. B Lymphocyte. lipid raft. PDK1. CD79A. CD79B. PKC θ. PKC b. CBM complex. CBM complex. CARMA1. CARMA1. MALT1. MALT1. MALT1. MALT1.
E N D
Figure 1 A B Ag presentingcell Ag presentingcell MHC/Ag B7-1/B7-2 MHC/Ag Immune Synapse BCR TCR CD28 CD19 T Lymphocyte B Lymphocyte lipid raft PDK1 CD79A CD79B PKCθ PKCb CBM complex CBM complex CARMA1 CARMA1 MALT1 MALT1 MALT1 MALT1 BCL10 BCL10 BCL10 BCL10 TRAF6 TRAF6 Caspase-8 Caspase-8 CARMA1 CARMA1 NEMO NEMO NEMO/I NEMO/I TAB2/3 TAB2/3 IKKβ IKKβ IKKα IKKα TAK1 TAK1 ADAP IκBα IκBα P P IκBα IκBα NF-κB NF-κB NF-κB NF-κB NF-κB NF-κB NF-κB-dependent transcription NF-κB-dependent transcription