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Skatole

Skatole. By: Patrick Kelsch and David Barlow. Characteristics of Skatole. Chemical Formula: C 9 H 9 N Molar Mass: 131.17 g/mole Density: 1.003g/cm^3 (solid) Melting Points: 95 °C, 368 K , and 203 °F Solubility in water: Insoluble

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Skatole

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  1. Skatole By: Patrick Kelsch and David Barlow

  2. Characteristics of Skatole • Chemical Formula: C9H9N • Molar Mass: 131.17 g/mole • Density: 1.003g/cm^3 (solid) • Melting Points: 95 °C, 368 K, and 203 °F • Solubility in water: Insoluble • Starts off as a fine white powder and turns brown as it ages.

  3. History and Uses of Skatole • Skatole was discovered by a German Physician named Ludwig Brieger in 1877. • It is found in feces, beets, and coal tar. • Skatole has a strong, smelly odor in large concentrations. In small concentrations it smells like flowers. • Skatole is used in perfumes, and fragrances. • Orchid bees and certain mosquitoes are attracted to this scent.

  4. Health Effects • Skatole is 1 of many ingredients in cigarettes and is added for flavor. • Skatole causes fluid to get into the lung airspace of animals, this can result in lung failure. • Skatole attacks enzymes in Clara Cells and converts the cells to a reactive intermediate which damages the cells by forming protein adducts. Adducts are products of at least 2 molecules, involving 1 reaction resulting in 1 product containing all the atoms of all the elements.

  5. References • http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pageLabel=PP_ARTICLEMAIN&node_id=841&content_id=CNBP_029585&use_sec=true&sec_url_var=region1&__uuid=3e820c0f-42f0-4bcf-b27b-4603e7d9e7c0 • http://en.wikipedia.org/wiki/Skatole • http://www.absoluteastronomy.com/topics/Skatole • http://www.wolframalpha.com/entities/chemicals/skatole/bn/e8/0d/

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