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A.P. John Institute for Cancer Research

Founded in 1978 by Angelo P. John, Sr., the A.P. John Institute for Cancer Research is dedicated to advancing molecular biology research in the field of cancer. Explore our comprehensive overview of colorectal cancer and its risk factors.

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A.P. John Institute for Cancer Research

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  1. Welcome To A. P. John Institute for Cancer Research The A.P. John Institute for Cancer Research was founded in 1978 by Angelo P. John, Sr., a molecular biologist specializing in cancer research.

  2. Colorectal Cancer What is Colorectal Cancer? • The colon and rectum are parts of the body's digestive system and together form a long, muscular tube called the large intestine. The colon is the first 6 feet of the large intestine and the rectum is the last 8-10 inches. Treatment approaches differ between cancers of the colon or rectum. • Adenocarcinoma refers to cancer that begins in the cells that line the colon or large intestine and accounts for over 90%-95% of cancers originating in the colon. Other cancers, including carcinoid and leiomyosarcoma, also originate in the colon, but are not referred to as colon cancer. This treatment overview deals only with adenocarcinoma of the colon, which will be referred to as colon cancer.

  3. Colorectal Cancer Colorectal Cancer Risk Factors • There are ways to prevent colorectal cancer — screening tests are the most effective. Most cases of the disease begin as non-cancerous polyps (grape-like growths) on the lining of the colon and rectum. These polyps can become cancerous. • Removing these polyps can prevent colorectal cancer from ever developing. Approximately 90 percent of colorectal cancers and deaths are thought to be preventable.

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