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Other People’s Data

Explore the challenges of utilizing foreign medication data sources and learn how dataspace profiling can enhance medication data quality. This article discusses the RxSafe dataspace, standards for medication information, connectivity of RxNorm and NDF-RT, and the architectural framework for dataspace characterization and customization.

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Other People’s Data

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  1. Other People’s Data David Maier & Nicholas B. Rayner Department of Computer Science Portland State University CIDR 2007

  2. Foreign Dataspaces Data sources seem to appear by spontaneous generation Often up to someone else to interpret them Description can be minimal, lacking or wrong CIDR 2007

  3. RxSafe Dataspace Medication records Assisted living facilities, Primary care clinics, Hospital, Pharmacies Standards for medication information • National Drug Code Directory (NDCD), FDA, packaged drugs • RxNorm, NLM, describing clinical drugs • National Drug File – Reference Terminology (NDF-RT), VA, drug classes CIDR 2007

  4. RxNorm Published Structure[RxNorm: A Guide for the Perplexed, http://www.nlm.nih.gov/umls/rxnorm/rxnorm_guide.pdf] CIDR 2007

  5. National Drug File – Reference Terminology (NDF-RT) CIDR 2007

  6. Issues • Internal properties of sources What is a key, foreign key in NDCD • Generic vs. domain-specific structure • Comparability Tradename (NDCD) vs. Brand Name (RxNorm) CIDR 2007

  7. Connectivity: RxNorm and NDF-RT Classes for 54%of brand names (RxNorm of 11/16/05) CIDR 2007

  8. Dataspace Profiling Interactive tool suite (Dataspace Workbench) for dataspace characterization and customization CIDR 2007

  9. Architectural Framework Modules for different property types, with 3 components • Probe: property verification or inference <c1,hasForm,c2>c1=clinical drug, c2=dose form • Switch: customization that exploits property hasForm(Clinical_Drug, Dose_Form) • Check: ensure updates don’t invalidate Might be easier than probe CIDR 2007

  10. Example Module:Linking Through Equivalency CIDR 2007

  11. What’s the Benefit? SELECT DISTINCT i.scd, c.class FROM scd_ing AS i INNER JOIN scd_class AS c ON i.scd = c.scd WHERE i.scd IN ('Penicillin G 250000 UNT Oral Tablet', 'Ibuprofen 200 MG Oral Capsule', 'Acebutolol 400 MG Oral Capsule'); +--------------------------------+-----------------------+ | scd | class | +--------------------------------+-----------------------+ | Acebutolol 400 MG Oral Capsule | BETA-BLOCKERS/RELATED | +--------------------------------+-----------------------+ SELECT DISTINCT i.scd, c.class FROM scd_ing_lim AS i INNER JOIN scd_ing_lim_scd_class_equivlink AS c ON i.ing = c.ing WHERE i.scd IN ('Penicillin G 250000 UNT Oral Tablet', 'Ibuprofen 200 MG Oral Capsule', 'Acebutolol 400 MG Oral Capsule'); +-------------------------------------+------------------------------------+ | scd | class | +-------------------------------------+------------------------------------+ | Acebutolol 400 MG Oral Capsule | BETA-BLOCKERS/RELATED | | Ibuprofen 200 MG Oral Capsule | NONSALICYLATE NSAIS, ANTIRHEUMATIC | | Penicillin G 250000 UNT Oral Tablet | PENICILLIN G-RELATED PENICILLINS | +-------------------------------------+------------------------------------+ CIDR 2007

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