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S.1. A. s hScr. shHSP90 a. shHSP90 b. A549. PaTu2. A549. PaTu2. p=0.0241. p=0.0041. p=0.0396. p=0.0001. Panc1. SW480. U251. B. PRKD2. PRKD2. PRKD2. PARP. PARP. clv. PARP. clv. PARP. PARP. clv. caspase 9. clv. PARP. clv. caspase 9. clv. caspase 9. b - actin.
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S.1 A shScr shHSP90a shHSP90b A549 PaTu2 A549 PaTu2 p=0.0241 p=0.0041 p=0.0396 p=0.0001 Panc1 SW480 U251 B PRKD2 PRKD2 PRKD2 PARP PARP clv. PARP clv. PARP PARP clv. caspase 9 clv. PARP clv. caspase 9 clv. caspase 9 b-actin b-actin b-actin 0 0.01 0.1 1.0 0 0.1 0.5 1.0 µM 0 0.01 0.1 1.0 0 0.1 0.5 1.0 µM STA-9090 PU-H71 STA-9090 PU-H71 0 0.01 0.1 1.0 µM 0 0.1 0.5 1.0 STA-9090 PU-H71