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Objectives of the study

Long-term prognostic value of white coat hypertension: an insight from diagnostic use of both ambulatory and home blood pressure measurements. Reference : Mancia G, Bombelli M, Brambilla G, et al. Hypertension . 2013 May 28. Epub ahead of print. doi:10.1161/​HYPERTENSIONAHA.111.00690.

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Objectives of the study

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  1. Long-term prognostic value of white coat hypertension: an insight from diagnostic use of both ambulatory and home blood pressure measurements Reference: Mancia G, Bombelli M, Brambilla G, et al. Hypertension. 2013 May 28. Epub ahead of print. doi:10.1161/​HYPERTENSIONAHA.111.00690.

  2. Objectives of the study • To compare the risk of cardiovascular (CV) and all-cause mortality in normotensive (NT), white coat hypertensive (WCH), and sustained hypertensive (HT) patients. • To evaluate the risk of developing hypertension in WCH compared with NT patients.

  3. What is white coat hypertension? • White coat hypertension is the condition in which office, but not out-of-office, blood pressure (BP) is elevated. • Out-of-office BP could be ambulatory or home BP. • Office hypertension is diagnosed when office BP >140/90 mm Hg, while ambulatory BP is normal at <125/79 mm Hg and home BP is <132/83 mm Hg. • In this study, the WCH group is separated into two subgroups: • True WCH (both home and ambulatory BP are normal); • Partial WCH (home or ambulatory BP is normal, the other is elevated).

  4. A long-term study • Data was collected from 2051 randomly selected patients: office BP, ambulatory BP, and home BP measurements. • Analysis over a 16-year follow-up of CV and all-cause mortality.

  5. Increasing CV and all-cause mortality in WCH patients Rate of events Rate of events

  6. A larger proportion of WCH patients develop hypertension

  7. Conclusions • The risk of CV and all-cause mortality was significantly increased in WCH patients compared with normotensives, especially in partial WCH patients. • The guidelines of the European Society of Cardiology and the European Society of Hypertension suggest follow-up of WCH patients, and to treat them if needed. • The risk of developing hypertension is also elevated in WCH patients.

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