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(7) Cellular Respiration. Cellular Respiration. (E) Regulation of pathways through feedback inhibition. (A) Role of ATP & Phosphorylation. (C) The metabolic pathway of respiration: electron transport chain & ATP synthesis. (B)
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(7) Cellular Respiration Cellular Respiration (E) Regulation of pathways through feedback inhibition (A) Role of ATP & Phosphorylation (C) The metabolic pathway of respiration: electron transport chain & ATP synthesis (B) The metabolic pathway of respiration: Glycolysis and the citric acid cycle (D) Substrates for Respiration
Cellular Respiration (d) • State 5 alternative substrates for respiration and in which stage(s) they can be used
Glucose the substrate • Think of this paperclip as glucose • During cellular respiration, this glucose molecule is broken down. • But what if glucose was not available? Would the cell still be able to carry out respiration? • YES!!! • (if you said ‘no’ you just killed that organism! No respiration = no life!)
Alternative substrates:Carbohydrates Glucose : Maltose : Simple sugar Simple sugar Sucrose : Starch : Complex carbohydrate stored in plants Simple sugar • Starch and glycogen are broken down to glucose for use as a respiratory substrate. • Other sugar molecules can be converted to glucose or glycolysisintermediates for use as respiratory substrates. Glycogen : Complex carbohydrate stored in animals in the LIVER
Demo: Investigating the use of 3 different sugars as a respiratory substrate • Read pages 108 and 109 before setting up the experiment
Alternative substrates:Fats • Fats can also be broken down into 1 glycerol and 3 fatty acid molecules. • These are intermediates of glycolysis and the citric acid cycle.
Alternative substrates:Proteins • Proteinscan be broken down to amino acids and converted to intermediates of glycolysis and the citric acid cycle for use as respiratory substrates. • Proteins are only used as an energy source as a last resort when the body has used up all other respiratory substrates, such as carbohydrates and fats (in cases such as starvation or anorexia)
Tasks Copy diagrams: • 7.18 on page 107 • 7.19 on page 108 • Read the case study on page 110 and 111 • Make a summary note on ‘the use of respiratory substrates during exercise and starvation’
Cellular Respiration (d) • State 5 alternative substrates for respiration and in which stage(s) they can be used