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Osteoscoop - Issue N°246 – July 2012

Examination of nuclear receptor expression in osteoblast reveals Ror b as an important regulator of osteogenesis. Osteoscoop - Issue N°246 – July 2012. Osteoblast progenitor. Osteoblast differentiation. Pre-osteoblast. Runx2. OSX. Runx2 OSX. ALP Osteocalcin Col1 a. Mature osteoblasts.

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Osteoscoop - Issue N°246 – July 2012

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  1. Examination of nuclear receptor expression in osteoblast reveals Rorb as an important regulator of osteogenesis Osteoscoop - Issue N°246 – July 2012

  2. Osteoblast progenitor Osteoblast differentiation Pre-osteoblast Runx2 OSX Runx2 OSX ALP Osteocalcin Col1a Mature osteoblasts Bone formation

  3. Osteoblast progenitor Rorb Osteoblast differentiation Pre-osteoblast High expression - Rorb Rorb Low expression Runx2 OSX Runx2 OSX ALP Osteocalcin Col1a Mature osteoblasts Bone formation

  4. Osteoblast progenitor Rorb Rorb relative expression Osteoblast differentiation Pre-osteoblast High expression - Rorb Rorb Low expression Runx2 OSX Runx2 OSX ALP Osteocalcin Col1a Mature osteoblasts Young Aged Osteoporotic mice Bone formation

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