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Anesthesia for Orthopedic surgery. อรุณชัย นรเศรษฐกมล. Content. General consideration Age-specific orthopedic conditions Medical comorbidities Coexisting medication Specific consideration Positioning Bone cement Pneumatic tourniquet Fat embolism Deep vein thrombosis & Thromboembolism.
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Anesthesia for Orthopedic surgery อรุณชัย นรเศรษฐกมล
Content • General consideration • Age-specific orthopedic conditions • Medical comorbidities • Coexisting medication • Specific consideration • Positioning • Bone cement • Pneumatic tourniquet • Fat embolism • Deep vein thrombosis & Thromboembolism
Age-specific orthopedic condition • Young adult • ACL reconstruction, Rotator cuff • Elderly • Hip, Knee arthroplasty • Hip Fracture • Children • Congenital orthopedic surgery
Medical comorbidities • Elderly patients • Multiple organ dysfunction • Rheumatoid arthritis • Osteoarthritis • Ankylosing spondylitis
Rheumatoid arthritis problem should be aware • Cervical spine instability • IV access • Systemic involvement • Airway management • Spinal or epidural may be difficult • Positioning
Osteoarthritis ( OA)problem should be aware • Reduced joint movement • Airway management • IV access • Spinal or epidural may be difficult • Positioning • Concurrent analgesic therapy
Ankylosing spondylitis (AS)problem should be aware • Fix flexion deformity • Regional anesthesia may be difficult • Abnormal spread of local anesthetics
Coexisting medication • Antihypertensive drugs • Steroids • Aspirin • NSAIDs • Opioid analgesics • Immunosuppressive drugs
Positioning • Supine • Lateral • Prone • Beach chair • Fracture table
Why is positioning important? • Enable IV and catheter to remain patent • Enable monitors to function properly • Facilitates the surgeon’s approach • Patient safety
Supine • Patient on back • Arms on arm boards • Arm < 90 degrees • Arm is supinated ( palm up) • Place padding under elbow if able • Arm tucked • Check fingers • Check IV lines and SaO2 probe
Lateral • Body alignment • Keep neck in neutral position • Always place axillary roll • Place padding between knees • Place padding below lateral aspect of dependent leg
Lateral • Position arms to parallel to one another • Place padding between arms or place non-dependent arm on padded surface
Prone • Face down • Head placement • Head straight forward • ET tube placement and patency • Check bilateral eyes/ears for pressure points • Head turned • Check dependent eye/ear, ETT placement • Be aware of potential vascular occlusion
Prone • Arm placement • Tucked – similar to supine • Abducted • Check neck rotation and arm extension to avoid brachial plexus injury • Elbow are padded • Chest rolls • Iliac support • Padding in placed under iliac crests
Injury occuring from prolonged positioning • Eye compression in prone position • Skin breakdown due to prolonged positioning
Bone cement Polymethylmethacrylate: MMA
Liquid MMA monomer + MMA powder intramedullary pressure high medullary content into circulation (fat, marrow, thrombus, air, bone cement) Embolization to the lung unbound MMA monomer Absorbing into the circution Vasodilation
Bone cement implantation syndrome ( BCIS) • Release of vasoactive and myocardial depressant substances • Intravascular thrombin generation in the lungs • Direct vasoactive effects of absorbed MMA • Acute pulmonary microembolization
Clinical presentation • Fever • Hypoxia • Hypotension • Tachycardia • Dysrhythmia • Mental status change • Dyspnea • End tidal CO2 decrease • Right ventricular failure and cardiac arrest
Management • Supportive care • Monitoring vital signs • O2 supplement • IV fluid • Vasopressor
Pneumatic tourniquet • No more than 2 hours • 100 mmHg above systolic blood pressure • 250 mmHg for arm • 350 mmHg for leg
Pneumatic tourniquet • Advantage • Eliminate intraoperative bleeding • Disadvantages • Neurologic effect • Muscle change • Systemic effects of the tourniquet inflation • Syeyemic effects of the tourniquet release
Neurologic effects • Tourniquet pain and hypertension If > 45-60 mins • Neurapraxia if > 2 hours • Nerve injury at the skin level the edge of the tourniquet
Muscle changes • Cellular hypoxia • Cellular acidosis • Endothelial capillary leak • Limb becomes colder
Systemic effect of tourniquet inflation • Arterial pressure elevated
Systemic effect of tourniquet release • Transient fall in core temperature • Transient metabolic acidosis • Release of acid metabolites into central circulation • Transient fall in arterial pressure • Transient increase in EtCO2
Prevention • Select patients • Wide, low-pressure cuff • Apply the lowest pressure to prevent bleeding • Limit time to 2 hours • Set maximum pressure • Arm 50-75 mmHg above systolic • Leg 75-100 mmHg above systolic • Adequate padding underneath
Fat embolism • The mechanical theory • The biochemical theory
Injury of the long bone, pelvis or surgery that increases intramedullary pressure Force large fat droplets into the systemic venous circulation Embolizing to the right heart and lung pulmonary hypertension
Clinical finding • Cardiovascular • Persistent tachycardia, hypotension • Respiratory • Dyspnea hypoxia hemoptysis • Cerebral • Delirium stupor seizure coma • Ophthalmic • Retinal hemorrhage • Cutaneous • petechiae • Other • Jaundice fever
Treatment • Prophylactic • Early stabilization of the fracture • Supportive • Respiratory care • Maximize O2, ventilation • Invasive monitor • Volume status • Inotrope • High dose corticosteroid
Deep vein thrombosis & Thromboembolismlower extremities, pelvis • Major pathophysiological mechanism • Venous stasis • Hypercoagulable state • Endothelial damage
Risk Factor • Obesity • Age > 60 years • Procedure > 30 mins • Use of tourniquet • Lower extremities fracture • Immobilization > 4 days
Prevention • Prophylactic anticoagulant • Low dose heparin • Warfarin • LMWH • Intermittent pneumatic compression • Neuraxial anesthesia reduce thromboembolic complication
Major orthopedic procedure • Total hip replacement • Fracture of the hip • Total knee replacement • Spinal surgery
Hip surgery • Patient • Limit ability to exercise • Cardiovascular function can be difficult to assess • Elderly with systemic disease, OA,RA • Blood loss • Use of hypotensive technique or reginal anesthesia reduces blood loss
Positioning • Mostly lateral decubitus position • Ventilation perfusion mismatch • Neurovascular problem
Potentially life-threatening complication • Bone cement implantation syndrome • Intra and postoperative hemorrhage • Venous thromboembolism