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The theme of the lecture : “ Chronic obstructive pulmonary disease. Bronchial asthma. Ethiology. Clinical pattern. Daignostics. Complications. Principles of treatment. ". Ass-prof.N.Bilkevych. The syndrome of bronchial obstruction. Obstructio (lat.) – barrier, obstracle.
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The theme of the lecture:“Chronic obstructive pulmonary disease. Bronchial asthma. Ethiology. Clinical pattern. Daignostics. Complications. Principles of treatment." Ass-prof.N.Bilkevych
The syndrome of bronchial obstruction • Obstructio (lat.) – barrier, obstracle. • Causes of bronchial obstruction: • - accumulation of fluid in fine bronchi; • - edema of bronchial mucosa; • - spasm of bronchial smooth muscles; • - poor elasticity of lungs.
Bronchial asthma Asthma is a bronchial hypersensitivity disorder characterized by reversible airway obstruction, produced by a combination of mucosal edema, constriction of the bronchial musculature, and excessive secretion of viscid mucus, causing mucous plugs. Essentials of Diagnosis: • Recurrent acute attacks of dyspnea, cough, and mucoid sputum, usually accompanied by wheezing. • Prolonged expiration with generalized wheezing and musical rales. • Bronchial obstruction reversible by drugs
Ethiology • 40-80 % of patients has heredital predisposition • Acquired ethiological factors • Domestic allergens • ( dust, insect allergens, fungi, animal wool, epidermis) • Environmental allergens • ( fungi, insect allergens, pollen etc) • Food allergy • ( milk, flour, fish, chemical admixtures to food) • drugs • ( antibiotics, enzymes, aspirin) • bacterial allergens • ( neisseria, Staphylococcus aureus, Candida albicans, mycoplasma, helmints)
Endoscopic findings: hyperemia, edema of bronchial mucosa, hypersecretion