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Suicidal Behaviour. Dr E Cassidy CUH January 2011. Terminology. Suicide. Death by individual who died “intentional” act or omission “completed” rather than “successful”. Self-Harm. Attempted Suicide Deliberate Self-Harm Parasuicide Self-Poisoning or Self-Injury Self-Mutilitation
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Suicidal Behaviour Dr E Cassidy CUH January 2011
Suicide • Death • by individual who died • “intentional” • act or omission • “completed” rather than “successful”
Self-Harm • Attempted Suicide • Deliberate Self-Harm • Parasuicide • Self-Poisoning or Self-Injury • Self-Mutilitation • Everything that doesn’t involve death – a behaviour not a diagnosis
Deaths classified as suicide in Ireland (1996-2009) Year 2008 and 2009 figures are provisional
Trends in undetermined deaths in Ireland (1996-2009) Year 2008 and 2009 figures are provisional
SUICIDE IN IRELAND • 500 per year • Peak M 20-24yo (34/100,000) • Peak F 45-54yo • Males @ 80% • Hanging, Poisoning, Drowning
Associations • Unemployed and retired • Divorced, never married • Certain Professions • Social class: I and V • Country variation lower in LDCs than Western; China (females) • Cultural variation • Seasonal variation • Highest April to June
Context • 1 in 6 leave notes • 1 in 2 have self harmed in the past • Majority have told someone • GP in previous month
Suicide and Psychiatry • ?90% suffer from some mental disorder • OCD may protect
Suicide and Schizophrenia • 10% mortality • Risks with • Early in illness • Males, younger • Relapses • Akathisia • Recent discharge • Paranoid ( Roy, 1982 )
Suicide and Depression • 5-15% lifetime risk • Melancholic depression • Psychotic depression • Family History
Incidence of deliberate self harm 2003-2009Total number of DSH episodes: 75,119Total number of individuals involved: 48,206
Main method of self harm (Average 2003-2009) Men Women Alcohol was involved in 46% and 38% of male and female acts, respectively
Intentions • Most neither want nor expect to die • 1/3 no thoughts • Cry for help • Escape • Often impulsive • 20-40% alcohol on board • Recent life stress • 20% repeats • Self-Mutilation • Punishment, Relieve tension
Associations • Separated and divorced • Low Socioeconomic status • Urban > Rural • Childhood disadvantage • Lack of Social Support • Lack of Religious affiliation • Collective (Princess Di effect, clustering) • Availability of means (paracetamol)
Cumulative probability of repeated DSH by DSH method and number of previous episodes Self-cutting & overdose Self-cutting only Other Attempted drowning Attempted hanging Drug overdose only Four previous DSH presentations Three previous DSH presentations Two previous DSH presentations One previous DSH presentation No previous DSH presentation
Factors associated with repetitionindependent of previous repetition Women aged 35-44 years had the highest risk of repetition (+33%) Among women, those who engaged in self-cutting only (+57%) and those with self-cutting with drug overdose (+48%) had the highest risk of repetition Among men, those engaging in self-cutting in combination with drug overdose had the highest risk (+49%)
Vulnerability – Stress • Vulnerability • Family history • Impulsive/aggressive personality traits • Childhood adversity/abuse • Hopelessness • Over generalised autobiographical recall • Stress • Life and esp interpersonal stress • Physical illness • Failed Inhibition • Alcohol and Drugs • Head Injury/ cognitive impairment • Lack of Adaptive Coping • social support, problem solving ability • Maladaptive coping • with alcohol, drugs (disinhibition)
Neurobiology • Serotonin: • Low 5-HIAA in CSF • Reduced frontal 5-HT2A receptor biding • 5HT is involved in impulsivity • 5-HTTLP predicts self-harm following life stress • HPA axis • Hyperactivity predicts self-harm / completion in depressives • Cholesterol • Low cholesterol predicts • Prefrontal Cortex • Failed response inhibition
Risk of Repetition • Think of risk as immediate and long term • Characteristics of attempt • Characteristics of person • Underlying psychiatric or physical disorder
Repetition and Suicide • 15% repeat by 1 year • 10%% suicide at long-term outome • Lethal prior method • Psychiatric disorder • Older males • Social isolation • Repeated self-harm • Avoiding discovery at time of self-harm • Strong suicidal intent • Substance misuse (especially in young people) • Hopelessness • Poor physical health
Asking about suicide • Asking about it does NOT increase the risk • It may decrease it! • But do it sensitively
Ask sensitively • Many people… • After what you’ve told me… • How do you think things will turn out ? • Do you ever wish you would never wake up ? • Have you thought about ending it all ? • What would you do ?
Assess suicidal risk • Current plans and intent • Availability • How far down the path have they gone • Why not yet • Current mental state • Previous attempts • Planning, precautions • Dangerousness (real and perceived) • What happened • Supports and ability to access them
Initial Management • Treat mental disorder • Address needs • Alcohol • Finance • Relationships • Give crisis contact details
Prevention • Complex public health initiatives • ? Reduce alcohol • Identify and treat more Depression • Lithium in Bipolar disorder • Clozapine in Schizophrenia • DBT in Borderline PD
NATIONAL CONFIDENTIAL INQUIRYINTO SUICIDE AND HOMICIDEBY PEOPLE WITH MENTAL ILLNESS England and Wales Annual report 2009
Patient Suicide • 26% suicides had contact with mental health services in the 12 months prior • Suicides less common following non-compliance/loss of contact with services • 14% of all suicides are Psychiatric Inpatients • 70% of these occurred off the ward • Inpatient suicides falling • Fallen by 1/3 (50% less hanging/strangulation) • Belts, shoelaces, sheets, towels • Removal of non-collapsible curtain rails 2002
Psychiatric diagnosis Affective disorder (534) Schizophrenia (198 - stable) Personality disorder 104 - (fallen) Alcohol Dependence (83 - fallen) Drug Dependence (24 - fallen) Other (176)
Method Hanging, OD, Jumping Hanging, jumping increased Overdose, CO poisoning decreased Drowning, firearms and burning stable