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PARVOVIRIDAE. PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mail Web site. LEARNING OBJECTIVES Students should be able to:.
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PARVOVIRIDAE PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mailWeb site
LEARNING OBJECTIVESStudents should be able to: • Relate the pathogenesis of feline infectious enteritis virus to its control • Explain the origins of canine parvovirus type 2 and its role in canine disease • Describe the importance and control of porcine parvovirus as a reproductive pathogen • List the species and disease conditions in which papilloma viruses are implicated
FELINE PARVOVIRUS DISEASE AND PATHOGENESIS:
FELINE PARVOVIRUS DIAGNOSIS:
FELINE PARVOVIRUS HOST RANGE : All felidae; mustelidae (mink) and some procyonidae (racoons and panda).
FELINE PARVOVIRUS ANTIGENICITY & CONTROL:
CANINE PARVOVIRUSTYPE 2 DISEASE AND PATHOGENESIS: Infection via oropharyngeal route followed by viraemia. Initially, there were two distinct syndromes associated with CPV-2: (1) targeted at rapidly dividing myocardial cells, (2) at the rapidly dividing cells in the crypt epithelium of the small intestine.
CANINE PARVOVIRUSTYPE 2 DIAGNOSIS:
CANINE PARVOVIRUSTYPE 2 HOST RANGE Dogs (but CPV-2a & 2b can cause disease in cats - see below)
CANINE PARVOVIRUSTYPE 2 ANTIGENICITY & CONTROL:
PORCINE PARVOVIRUS DISEASE AND PATHOGENESIS
PORCINE PARVOVIRUS HOST RANGE: pigs
PORCINE PARVOVIRUS EPIZOOTIOLOGY:
PORCINE PARVOVIRUS ANTIGENICITY & CONTROL:
SUMMARY • Cause serious diseases in cats (enteritis/ panleucopenia), dogs (myocarditis/ enteritis) and pigs (SMEDI). • Pathogenesis is related to the requirement for rapidly dividing cells for virus replication • Vaccines available for each disease which prevent viraemia & hence destruction of rapidly dividing cells.