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Phase 2. Treatment-Experienced. Glecaprevir - Pibrentasvir in HCV GT 1 & Prior DAA Treatment MAGELLAN-1 (Part 1). Source: Poordad F, et al. Hepatology. 2017;66:389-97. Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA Treatment MAGELLAN-1 (Part 1) : Study Features.
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Phase 2 Treatment-Experienced Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1) Source: PoordadF, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Study Features Source: Poordad F, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Treatment Regimens 0 12 24 Week GT 1 n = 50 Glecaprevir: 200 mgPibreantasvir: 80 mg SVR12 n = 6 Glecaprevir: 300 mgPibreantasvir: 120 mg Ribavirin: 800 mg n = 22 SVR12 Glecaprevir: 200 mgPibreantasvir: 120 mg SVR12 n = 22 Source: Poordad F, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Baseline Characteristics GLE-PIB= glecaprevir-pibrentasvir; RBV = ribavirin; BMI = body mass index Source: Poordad F, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Baseline Characteristics GLE-PIB= glecaprevir-pibrentasvir Source: Poordad F, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Study Design 6/6 21/22 19/22 Source: Poordad F, et al. Hepatology. 2017;66:389-97.
Glecaprevir-Pibrentasvir in HCV GT 1 & Prior DAA TreatmentMAGELLAN-1 (Part 1): Conclusions Source: Poordad F, et al. Hepatology. 2017;66:389-97.
This slide deck is from the University of Washington’s Hepatitis C Online and Hepatitis Web Study projects. Hepatitis C Onlinewww.hepatitisc.uw.edu Hepatitis Web Studyhttp://depts.washington.edu/hepstudy/ Funded by a grant from the Centers for Disease Control and Prevention.