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DFPP

Figure e-1. Clinical Course of the Patient. Phenytoin. Carbamazepine. Gabapentin. Midazolam. Immnosuppressive treatments. mPSL. rituximab. DFPP. Partial seizures Tonic seizures Hiccups Apneas. Generalized seizures. Seizures. Totally unresponsive. Consciousness. Paranoia.

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DFPP

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  1. Figure e-1. Clinical Course of the Patient Phenytoin Carbamazepine Gabapentin Midazolam Immnosuppressive treatments mPSL rituximab DFPP Partial seizures Tonic seizures Hiccups Apneas Generalized seizures Seizures Totally unresponsive Consciousness Paranoia Hallucination Psychiatric symptoms CSF findings 1 54 52.9 0.48 3 46 31.5 1 38 41.2 0.56 Cells (/mm3) TP (mg/dL) IgG (μg/mL) IgG index 10 45 55.0 0.52 30 78 168.3 1.0 2 36 48.0 0.55 Anti-NR1/NR2 heteromer antibodies CSF Serum X 320 positive X 10 negative Cognitive function Hasegawa Dementia Scale-Revised 28/30 28/30 79 Total IQ (WAIS-R) admission day 30 day 60 day 90 day 120 Abbreviations: mPSL, methylprednisolone; DFPP, double-filtration plasmapheresis; TP, total protein levels, WAIS-R, Wechsler Adult Intelligence Scale-Revised.

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