420 likes | 725 Views
HIV Opportunistic infections. OIs- 10. OIs are the most common presentation of chronic treated HIV infection. OIs– 10. No. OIs - 20. OIs usually present when CD4< 300. OIs – 20. No usually when CD4 < 200. OIs - 30. The most common OI in HIV infection. OI – 30. Oral candidiasis.
E N D
OIs- 10 • OIs are the most common presentation of chronic treated HIV infection
OIs– 10 • No
OIs - 20 • OIs usually present when CD4< 300
OIs – 20 • No usually when CD4 < 200
OIs - 30 • The most common OI in HIV infection
OI – 30 • Oral candidiasis
OI - 40 • Name 2 of the most life threatening OIs
OI– 40 • PCP • Cryptococcosis
OI- 50 • CMV presents when CD4 < 50 and prophylaxis with antivirals should be started
OI– 50 • Antivirals are not part of prophylaxis for HIV related OIs
PCP - 10 • One of the most common causes of death from AIDS in 80s
PCP – 10 • Yes
PCP- 20 • PJP is a common environmental parasite
MHC – 20 • IT is a fungus not a parasite
PCP- 30 • Drug of choice for PCP prophylaxis and alternative if patient has allergy
PCP– 40 • Diagnostic test of choice for PCP
PCP- 40 • Diagnostic test of choice for PCP
PCP– 40 • Sputum DFA for PCP
PCP- 50 • One scenario that patient should stay on prophylaxis for PCP for life
PCP– 50 • If patient had episode of PCP with CD4 > 200
Cryptococcus- 10 • The most common manifestation of cryptococcus infection
Cryptococcus– 10 • CNS infection
Cryptococcus- 20 • Why frequent LPs are needed with crypto meningitis?
Cryptococcus– 20 • Increased ICP
Cryptococcus - 30 • Name two diagnostic tests for Cryptococcus infection
Cryptococcus– 30 • Cryptococcus antigen • Fungal culture
Cryptococcus - 40 • Name the induction therapy for Cryptococcus
Cryptococcus– 40 • Amphotericin + 5FC
Cryptococcus - 50 • This regimen has been used in resource poor countries for treatment of Cryptococcus infection
Cryptococcus– 50 • High doses fluconazole (>800 mg) plus 5FC
Toxoplasma- 10 • Name 2 presentation of toxoplasmosis
Toxoplasma- – 10 • Fever, headaches, seizures, no clinical manifestations
Toxoplasma - 20 • A common carrier of toxoplasma (animal)
Toxoplasma– 20 • Cat
Toxoplasma - 30 • The antibiotic that is used for prophylaxis for Toxoplasma is also effective for other OIs
Toxoplasma– 30 • Bactrim is also effective against PCP
Toxoplasma- 40 • Name alternative antibiotics for Toxoplasma (if there is allergy to the drug of choice)
Toxoplasma– 40 • Clindamycin, pyrimethamine
Toxoplasma- 50 • Duration of prophylaxis for toxoplasma
Toxoplasma- 50 • Discontinue ppx when CD4>200 > 3 months